Partially covered, self-expandable metal stents with
anti-reflux valves for malignancies comprising hilar region

a 2015

Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region

ANDRAŠINA, Tomáš, Sung Kwon KANG, Jong Ho MOON, Tomáš GROLICH, Michal CRHA et. al.

Basic information

Original name

Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region

Authors

ANDRAŠINA, Tomáš (703 Slovakia, guarantor, belonging to the institution), Sung Kwon KANG (410 Republic of Korea), Jong Ho MOON (410 Republic of Korea), Tomáš GROLICH (203 Czech Republic, belonging to the institution) and Michal CRHA (203 Czech Republic)

Edition

9th Meeting of the Society of Gastrointestinal Intervention, 2015

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Republic of Korea

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/15:00084697

Organization unit

Faculty of Medicine

Keywords in English

self expandable metal; stent; biliary antireflux valve

Abstract

V originále

Objective: To prove feasibility of percutaneous parallel implantation of partially covered, self-expandable metal stents (PC-SEMS) with antireflux valves (AR valves) in in-vivo model. Method: The novel design of PC-SEMS suitable for patients with hilar malignancies was developed. For percutaneous implantation of stent with AR valve, specific type of introducer is needed to prevent closing and crumpling of valve during implantation procedure. Stent is half covered with e-PTFE membrane, also forming AR valve. Proximal half of the stent is bare to allow flow of bile from segmental branches of biliary tree arising in hilar region. In-vivo experiment was chosen to test safe deployment of two PC-SEMS with AR valve. Parallel and synchronous implantation of stents was used in cross-bred piglet model. The procedure was performed under general anaesthesia with simulation of percutaneous approach. Open laparotomic view of duodenum was used for observation of AR valve. One week later the experimental model was euthanized and autopsy was performed to assess stent patency, presence of intraluminal content and function of AR valve. Results: The implantation of SEMS with AR valve is performed with an extra step. By retrieving of stent introducer sheath, a metal bumper which maintains the open position of antireflux valve is opened. The extra step of recapturing metal bumper is needed to safely remove the introducer system. For the synchronous and parallel implantation of two stents whole process of implantation was completed without collision or affecting the AR valve system. The extra step prolonged the procedure insignificantly (8 and 9 seconds). The autopsy of model proved full patency of SEMS and AR valve. No intraluminal content was found inside the stents. Conclusion: The new self expandable partially covered stent with antireflux valve is suitable for parallel and synchronous percutaneous implantation. No significant reflux was observed during experimental period.

Links

ROZV/20/LF/2015, interní kód MU

Name: LF - Příspěvek IP 2015

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

ANDRAŠINA, Tomáš, Sung Kwon KANG, Jong Ho MOON, Tomáš GROLICH and Michal CRHA. Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region. In 9th Meeting of the Society of Gastrointestinal Intervention. 2015.

@proceedings{1317146,
   author = {Andrašina, Tomáš and Kang, Sung Kwon and Moon, Jong Ho and Grolich, Tomáš and Crha, Michal},
   booktitle = {9th Meeting of the Society of Gastrointestinal Intervention},
   keywords = {self expandable metal; stent; biliary antireflux valve},
   language = {eng},
   title = {Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region},
   year = {2015}
}

TY  - CONF
ID  - 1317146
AU  - Andrašina, Tomáš - Kang, Sung Kwon - Moon, Jong Ho - Grolich, Tomáš - Crha, Michal
PY  - 2015
TI  - Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region
KW  - self expandable metal
KW  - stent
KW  - biliary antireflux valve
N2  - Objective: To prove feasibility of percutaneous parallel implantation of partially covered, self-expandable metal stents (PC-SEMS) with antireflux valves (AR valves) in in-vivo model. Method: The novel design of PC-SEMS suitable for patients with hilar malignancies was developed. For percutaneous implantation of stent with AR valve, specific type of introducer is needed to prevent closing and crumpling of valve during implantation procedure. Stent is half covered with e-PTFE membrane, also forming AR valve. Proximal half of the stent is bare to allow flow of bile from segmental branches of biliary tree arising in hilar region. In-vivo experiment was chosen to test safe deployment of two PC-SEMS with AR valve. Parallel and synchronous implantation of stents was used in cross-bred piglet model. The procedure was performed under general anaesthesia with simulation of percutaneous approach. Open laparotomic view of duodenum was used for observation of AR valve. One week later the experimental model was euthanized and autopsy was performed to assess stent patency, presence of intraluminal content and function of AR valve. Results: The implantation of SEMS with AR valve is performed with an extra step. By retrieving of stent introducer sheath, a metal bumper which maintains the open position of antireflux valve is opened. The extra step of recapturing metal bumper is needed to safely remove the introducer system. For the synchronous and parallel implantation of two stents whole process of implantation was completed without collision or affecting the AR valve system. The extra step prolonged the procedure insignificantly (8 and 9 seconds). The autopsy of model proved full patency of SEMS and AR valve. No intraluminal content was found inside the stents. Conclusion: The new self expandable partially covered stent with antireflux valve is suitable for parallel and synchronous percutaneous implantation. No significant reflux was observed during experimental period.
ER  -

ANDRAŠINA, Tomáš, Sung Kwon KANG, Jong Ho MOON, Tomáš GROLICH and Michal CRHA. Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region. In \textit{9th Meeting of the Society of Gastrointestinal Intervention}. 2015.

Detailed Information on Publication Record