J 2017

Cleft palate caused by congenital teratoma

VEYSSIÈRE, Alexis, Libor STREIT, Hamady TRAORÉ and Hervé BÉNATEAU

Basic information

Original name

Cleft palate caused by congenital teratoma

Authors

VEYSSIÈRE, Alexis, Libor STREIT, Hamady TRAORÉ and Hervé BÉNATEAU

Edition

Paediatrics and International Child Health, Abingdon, Taylor & Francis LTD, 2017, 2046-9047

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 1.528

Organization unit

Faculty of Medicine

DOI

UT WoS

000395629100012

Keywords in English

Benign teratoma; Cleft palate

Tags

Tags

International impact, Reviewed
Změněno: 16/3/2018 15:13, Soňa Böhmová

Abstract

V originále

A cleft palate results from incomplete fusion of the lateral palatine processes, the median nasal septum and the median palatine process. This case report describes a rare case of congenital teratoma originating from the nasal septum that may have interfered with the fusion of the palatal shelves during embryonic development, resulting in a cleft palate. An infant girl was born at 40 weeks of gestation weighing 3020 g with a complete cleft palate associated with a large central nasopharyngeal tumour. Computed tomography (CT) of the head showed a well defined mass of mixed density. The tumour was attached to the nasal septum in direct contact with the cleft palate. A biopsy confirmed the teratoma. Tumour resection was performed at 5 months, soft palate reconstruction at 7 months and hard palate closure at 14 months. There was no sign of local recurrence 1 year later. Most teratomas are benign and the prognosis is usually good. However, recurrence is not rare if germ cell carcinomatous foci are present within the teratoma. For these reasons, we advocate the use of a two-stage procedure in which closure of the cleft palate is postponed until histological examination confirms complete excision of the teratoma.