VEYSSIÈRE, Alexis, Libor STREIT, Hamady TRAORÉ and Hervé BÉNATEAU. Cleft palate caused by congenital teratoma. Paediatrics and International Child Health. Abingdon: Taylor & Francis LTD, 2017, vol. 37, No 1, p. 66-69. ISSN 2046-9047. Available from: https://dx.doi.org/10.1179/2046905515Y.0000000057.
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Basic information
Original name Cleft palate caused by congenital teratoma
Authors VEYSSIÈRE, Alexis, Libor STREIT, Hamady TRAORÉ and Hervé BÉNATEAU.
Edition Paediatrics and International Child Health, Abingdon, Taylor & Francis LTD, 2017, 2046-9047.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.528
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1179/2046905515Y.0000000057
UT WoS 000395629100012
Keywords in English Benign teratoma; Cleft palate
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 16/3/2018 15:13.
Abstract
A cleft palate results from incomplete fusion of the lateral palatine processes, the median nasal septum and the median palatine process. This case report describes a rare case of congenital teratoma originating from the nasal septum that may have interfered with the fusion of the palatal shelves during embryonic development, resulting in a cleft palate. An infant girl was born at 40 weeks of gestation weighing 3020 g with a complete cleft palate associated with a large central nasopharyngeal tumour. Computed tomography (CT) of the head showed a well defined mass of mixed density. The tumour was attached to the nasal septum in direct contact with the cleft palate. A biopsy confirmed the teratoma. Tumour resection was performed at 5 months, soft palate reconstruction at 7 months and hard palate closure at 14 months. There was no sign of local recurrence 1 year later. Most teratomas are benign and the prognosis is usually good. However, recurrence is not rare if germ cell carcinomatous foci are present within the teratoma. For these reasons, we advocate the use of a two-stage procedure in which closure of the cleft palate is postponed until histological examination confirms complete excision of the teratoma.
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