Factors Affecting Antioxidant Response in Fish from a Long-term
Mercury-Contaminated Reservoir

J 2015

Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir

SEVCIKOVA, M., H. MODRA, J. BLAHOVA, R. DOBSIKOVA, Jiří KALINA et. al.

Basic information

Original name

Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir

Authors

SEVCIKOVA, M. (203 Czech Republic), H. MODRA (203 Czech Republic), J. BLAHOVA (203 Czech Republic), R. DOBSIKOVA (203 Czech Republic), Jiří KALINA (203 Czech Republic, guarantor, belonging to the institution), O. ZITKA (203 Czech Republic), R. KIZEK (203 Czech Republic) and Z. SVOBODOVA (203 Czech Republic)

Edition

Archives of Environmental Contamination and Toxicology, New York, Springer-Verlag, 2015, 0090-4341

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10600 1.6 Biological sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.039

RIV identification code

RIV/00216224:14110/15:00084936

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s00244-015-0213-0

UT WoS

000362666700006

Keywords in English

TROUT ONCORHYNCHUS-MYKISS; SALMON SALMO-SALAR; OXIDATIVE STRESS; LIZA-AURATA; DIETARY METHYLMERCURY; LIPID-PEROXIDATION; AQUATIC ORGANISMS; BIOACCUMULATION; GLUTATHIONE; EXPOSURE

Abstract

V originále

The objective of this work was to evaluate antioxidant defence and oxidative damage in organs (liver, gills, kidney, and brain) of five fish species (Aspius aspius, Esox lucius, Sander lucioperca, Abramis brama, Rutilus rutilus) from the long-term mercury-contaminated Skalka Reservoir in the Czech Republic. Special emphasis was placed on a comprehensive assessment of the factors that may affect the antioxidant response to mercury in fish. Antioxidant enzymes (glutathione reductase, glutathione peroxidase, and glutathione-S-transferase) did not significantly respond to mercury contamination. Levels of the analysed enzymes and oxidative damage to lipids were predominantly determined by a separate organ factor or species factor, or by the combination of both (p < 0.001). Levels of total glutathione and the reduced/oxidized glutathione ratio were influenced by mercury contamination in combination with their specific organ distribution (p < 0.001). Our results suggest that species and type of organ alone or in combination are more important factors than chronic exposure to mercury contamination with respect to effects on antioxidant defence in fish under field conditions. Our findings suggest that the main antioxidant defensive mechanism in fish from the studied long-term mercury contaminated site was the inter-tissue distribution of glutathione.

Citovat

SEVCIKOVA, M., H. MODRA, J. BLAHOVA, R. DOBSIKOVA, Jiří KALINA, O. ZITKA, R. KIZEK and Z. SVOBODOVA. Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir. Archives of Environmental Contamination and Toxicology. New York: Springer-Verlag, 2015, vol. 69, No 4, p. 431-439. ISSN 0090-4341. Available from: https://dx.doi.org/10.1007/s00244-015-0213-0.

@article{1318802,
   author = {Sevcikova, M. and Modra, H. and Blahova, J. and Dobsikova, R. and Kalina, Jiří and Zitka, O. and Kizek, R. and Svobodova, Z.},
   article_location = {New York},
   article_number = {4},
   doi = {http://dx.doi.org/10.1007/s00244-015-0213-0},
   keywords = {TROUT ONCORHYNCHUS-MYKISS; SALMON SALMO-SALAR; OXIDATIVE STRESS; LIZA-AURATA; DIETARY METHYLMERCURY; LIPID-PEROXIDATION; AQUATIC ORGANISMS; BIOACCUMULATION; GLUTATHIONE; EXPOSURE},
   language = {eng},
   issn = {0090-4341},
   journal = {Archives of Environmental Contamination and Toxicology},
   title = {Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir},
   volume = {69},
   year = {2015}
}

TY  - JOUR
ID  - 1318802
AU  - Sevcikova, M. - Modra, H. - Blahova, J. - Dobsikova, R. - Kalina, Jiří - Zitka, O. - Kizek, R. - Svobodova, Z.
PY  - 2015
TI  - Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir
JF  - Archives of Environmental Contamination and Toxicology
VL  - 69
IS  - 4
SP  - 431-439
EP  - 431-439
PB  - Springer-Verlag
SN  - 00904341
KW  - TROUT ONCORHYNCHUS-MYKISS
KW  - SALMON SALMO-SALAR
KW  - OXIDATIVE STRESS
KW  - LIZA-AURATA
KW  - DIETARY METHYLMERCURY
KW  - LIPID-PEROXIDATION
KW  - AQUATIC ORGANISMS
KW  - BIOACCUMULATION
KW  - GLUTATHIONE
KW  - EXPOSURE
N2  - The objective of this work was to evaluate antioxidant defence and oxidative damage in organs (liver, gills, kidney, and brain) of five fish species (Aspius aspius, Esox lucius, Sander lucioperca, Abramis brama, Rutilus rutilus) from the long-term mercury-contaminated Skalka Reservoir in the Czech Republic. Special emphasis was placed on a comprehensive assessment of the factors that may affect the antioxidant response to mercury in fish. Antioxidant enzymes (glutathione reductase, glutathione peroxidase, and glutathione-S-transferase) did not significantly respond to mercury contamination. Levels of the analysed enzymes and oxidative damage to lipids were predominantly determined by a separate organ factor or species factor, or by the combination of both (p < 0.001). Levels of total glutathione and the reduced/oxidized glutathione ratio were influenced by mercury contamination in combination with their specific organ distribution (p < 0.001). Our results suggest that species and type of organ alone or in combination are more important factors than chronic exposure to mercury contamination with respect to effects on antioxidant defence in fish under field conditions. Our findings suggest that the main antioxidant defensive mechanism in fish from the studied long-term mercury contaminated site was the inter-tissue distribution of glutathione.
ER  -

SEVCIKOVA, M., H. MODRA, J. BLAHOVA, R. DOBSIKOVA, Jiří KALINA, O. ZITKA, R. KIZEK and Z. SVOBODOVA. Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir. \textit{Archives of Environmental Contamination and Toxicology}. New York: Springer-Verlag, 2015, vol.~69, No~4, p.~431-439. ISSN~0090-4341. Available from: https://dx.doi.org/10.1007/s00244-015-0213-0.

Detailed Information on Publication Record