Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis - case report and review of the literature

ŘÍČNÁ, Dita, Martina LENGEROVÁ, Martina PALACKOVÁ, Markéta HADRABOVÁ, Iva KOCMANOVÁ, Barbora WEINBERGEROVÁ, Zdeněk PAVLOVSKÝ, Pavlína VOLFOVÁ, Jana BOUCHNEROVÁ, Jiří MAYER and Zdeněk RÁČIL. Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis - case report and review of the literature. Mycoses. Hoboken: Wiley-Blackwell, 2016, vol. 59, No 1, p. 48-55. ISSN 0933-7407. Available from: https://dx.doi.org/10.1111/myc.12421.

Basic information

• Original name: Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis - case report and review of the literature
• Authors: ŘÍČNÁ, Dita (203 Czech Republic, belonging to the institution), Martina LENGEROVÁ (203 Czech Republic, guarantor, belonging to the institution), Martina PALACKOVÁ (703 Slovakia, belonging to the institution), Markéta HADRABOVÁ (203 Czech Republic, belonging to the institution), Iva KOCMANOVÁ (203 Czech Republic), Barbora WEINBERGEROVÁ (203 Czech Republic, belonging to the institution), Zdeněk PAVLOVSKÝ (203 Czech Republic), Pavlína VOLFOVÁ (203 Czech Republic), Jana BOUCHNEROVÁ (203 Czech Republic, belonging to the institution), Jiří MAYER (203 Czech Republic, belonging to the institution) and Zdeněk RÁČIL (203 Czech Republic, belonging to the institution).
• Edition: Mycoses, Hoboken, Wiley-Blackwell, 2016, 0933-7407.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30200 3.2 Clinical medicine
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 2.252
• RIV identification code: RIV/00216224:14110/16:00089217
• Organization unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1111/myc.12421
• UT WoS: 000367095200009
• Keywords in English: Fusariosis; Fusarium proliferatum; PCR diagnostics; Real-time PCR
• Tags: EL OK, podil
• Tags: International impact, Reviewed

Abstract

Disseminated fusariosis is a life-threatening, invasive, opportunistic infection in immunocompromised patients, especially those with haematological malignancies. The prognosis is poor because these fungi are resistant to many of the available antifungal agents. We present a case of disseminated fusariosis caused by Fusarium proliferatum in a patient with severe aplastic anaemia complicated by a secondary infection of Aspergillus flavus, with a fatal outcome. We also review the documented Fusarium infections in immunocompromised hosts.

Links

• LM2015090, research and development project: Name: Český národní uzel Evropské sítě infrastruktur klinického výzkumu (Acronym: CZECRIN)

Investor: Ministry of Education, Youth and Sports of the CR

• MUNI/A/1180/2014, interní kód MU: Name: Nové přístupy ve výzkumu, diagnostice a terapii hematologických malignit II (Acronym: VýDiTeHeMa II)

Investor: Masaryk University, Category A