Busulphane and treosulphane in therapy of pediatric solid tumors

MAZÁNEK, Pavel, Ludmila MALÁŠKOVÁ, Tomáš KEPÁK and Peter MÚDRY. Busulphane and treosulphane in therapy of pediatric solid tumors. In XXV. Konference dětských hematologů a onkologů České a Slovenské republiky. 2015. ISBN 978-80-210-7958-8.

Basic information

Original name

Busulphane and treosulphane in therapy of pediatric solid tumors

Authors

MAZÁNEK, Pavel (203 Czech Republic, guarantor, belonging to the institution), Ludmila MALÁŠKOVÁ (203 Czech Republic), Tomáš KEPÁK (203 Czech Republic, belonging to the institution) and Peter MÚDRY (203 Czech Republic, belonging to the institution)

Edition

XXV. Konference dětských hematologů a onkologů České a Slovenské republiky, 2015

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Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/15:00085319

Organization unit

Faculty of Medicine

ISBN

978-80-210-7958-8

Keywords (in Czech)

busulfan; treosulfan; ewingův sarkom; neuroblastom; farmakokinetika

Keywords in English

busulfan; treosulfan; Ewing's sarcoma; neuroblastoma; pharmacokinetics

Tags

EL OK

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Abstract

V originále

Busulfan and treosulfan are strong alkylating agents with significant antitumor myeloablative and immunosupresive potential. Both these preparations are integral consolidation treatment of high-risk pediatric solid tumors, particularly neuroblastoma (NBL) and Ewing's sarcoma (ES) either at the time of primary therapy as well as in the treatment of relapse of these diseases.