The clinical phenomenology and associations of trick maneuvers
in cervical dystonia

J 2016

The clinical phenomenology and associations of trick maneuvers in cervical dystonia

FILIP, Pavel, Marek BALÁŽ, Rastislav ŠUMEC and Martin BAREŠ

Basic information

Original name

The clinical phenomenology and associations of trick maneuvers in cervical dystonia

Authors

FILIP, Pavel (703 Slovakia, belonging to the institution), Marek BALÁŽ (703 Slovakia, belonging to the institution), Rastislav ŠUMEC (703 Slovakia, belonging to the institution) and Martin BAREŠ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Neural Transmission, Wien, Springer Wien, 2016, 0300-9564

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Austria

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.392

RIV identification code

RIV/00216224:14110/16:00088837

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s00702-015-1488-z

UT WoS

000373162900014

Keywords in English

Sensory trick; Cervical dystonia; Botulinum toxin; Treatment effectiveness

Abstract

V originále

Sensory trick is an unusual clinical feature in cervical dystonia that attenuates disease symptoms by slight touch to a specific area of the face or head. Using a semi-quantitative questionnaire-based study of 197 patients with idiopathic cervical dystonia, we sought to determine probable pathophysiologic correlates, with the wider aim of examining its eventual clinical significance. The typical sensory trick, i.e., light touch, not necessitating the use of force leading to simple overpowering of dystonic activity, was present in 83 (42.1 %) patients. The vast majority of the patients required a specific sequence of sensorimotor inputs, including touch sensation on the face or different areas of the head, and also sensory and motor input of the hand itself. Deviations often led to a significant decrease in effectiveness and lack of expected benefit. Moreover, patients able to perform the maneuver reported compellingly higher subjective effect of botulinum toxin treatment (median 7 vs. 5 on a scale of 0–10; p\0.0001) and lower depression score (median 10 vs. 14 on the Montgomery Asberg Depression Rating scale; p\0.001). Overall, the results point to marked disruption of sensorimotor networks in cervical dystonia. The mechanism of the sensory trick action may be associated with balancing the abnormal activation patterns by specific sensorimotor inputs. Its presence may be considered a positive predictive factor for responsiveness to botulinum toxin treatment.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

NT13437, research and development project

Name: Mozeček, kognitivní dysfunkce a mechanismy kontroly pohybu a odhadu času u dystonie a schizofrenie.

Files attached

EL_1321929.pdf

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Citovat

FILIP, Pavel, Marek BALÁŽ, Rastislav ŠUMEC and Martin BAREŠ. The clinical phenomenology and associations of trick maneuvers in cervical dystonia. Journal of Neural Transmission. Wien: Springer Wien, 2016, vol. 123, No 3, p. 269-275. ISSN 0300-9564. Available from: https://dx.doi.org/10.1007/s00702-015-1488-z.

@article{1321929,
   author = {Filip, Pavel and Baláž, Marek and Šumec, Rastislav and Bareš, Martin},
   article_location = {Wien},
   article_number = {3},
   doi = {http://dx.doi.org/10.1007/s00702-015-1488-z},
   keywords = {Sensory trick; Cervical dystonia; Botulinum toxin; Treatment effectiveness},
   language = {eng},
   issn = {0300-9564},
   journal = {Journal of Neural Transmission},
   title = {The clinical phenomenology and associations of trick maneuvers in cervical dystonia},
   volume = {123},
   year = {2016}
}

TY  - JOUR
ID  - 1321929
AU  - Filip, Pavel - Baláž, Marek - Šumec, Rastislav - Bareš, Martin
PY  - 2016
TI  - The clinical phenomenology and associations of trick maneuvers in cervical dystonia
JF  - Journal of Neural Transmission
VL  - 123
IS  - 3
SP  - 269-275
EP  - 269-275
PB  - Springer Wien
SN  - 03009564
KW  - Sensory trick
KW  - Cervical dystonia
KW  - Botulinum toxin
KW  - Treatment effectiveness
N2  - Sensory trick is an unusual clinical feature in cervical dystonia that attenuates disease symptoms by slight touch to a specific area of the face or head. Using a semi-quantitative questionnaire-based study of 197 patients with idiopathic cervical dystonia, we sought to determine probable pathophysiologic correlates, with the wider aim of examining its eventual clinical significance. The typical sensory trick, i.e., light touch, not necessitating the use of force leading to simple overpowering of dystonic activity, was present in 83 (42.1 %) patients. The vast majority of the patients required a specific sequence of sensorimotor inputs, including touch sensation on the face or different areas of the head, and also sensory and motor input of the hand itself. Deviations often led to a significant decrease in effectiveness and lack of expected benefit. Moreover, patients able to perform the maneuver reported compellingly higher subjective effect of botulinum toxin treatment (median 7 vs. 5 on a scale of 0–10; p\0.0001) and lower depression score (median 10 vs. 14 on the Montgomery Asberg Depression Rating scale; p\0.001). Overall, the results point to marked disruption of sensorimotor networks in cervical dystonia. The mechanism of the sensory trick action may be associated with balancing the abnormal activation patterns by specific sensorimotor inputs. Its presence may be considered a positive predictive factor for responsiveness to botulinum toxin treatment.
ER  -

FILIP, Pavel, Marek BALÁŽ, Rastislav ŠUMEC and Martin BAREŠ. The clinical phenomenology and associations of trick maneuvers in cervical dystonia. \textit{Journal of Neural Transmission}. Wien: Springer Wien, 2016, vol.~123, No~3, p.~269-275. ISSN~0300-9564. Available from: https://dx.doi.org/10.1007/s00702-015-1488-z.

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