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@article{1321929, author = {Filip, Pavel and Baláž, Marek and Šumec, Rastislav and Bareš, Martin}, article_location = {Wien}, article_number = {3}, doi = {http://dx.doi.org/10.1007/s00702-015-1488-z}, keywords = {Sensory trick; Cervical dystonia; Botulinum toxin; Treatment effectiveness}, language = {eng}, issn = {0300-9564}, journal = {Journal of Neural Transmission}, title = {The clinical phenomenology and associations of trick maneuvers in cervical dystonia}, volume = {123}, year = {2016} }
TY - JOUR ID - 1321929 AU - Filip, Pavel - Baláž, Marek - Šumec, Rastislav - Bareš, Martin PY - 2016 TI - The clinical phenomenology and associations of trick maneuvers in cervical dystonia JF - Journal of Neural Transmission VL - 123 IS - 3 SP - 269-275 EP - 269-275 PB - Springer Wien SN - 03009564 KW - Sensory trick KW - Cervical dystonia KW - Botulinum toxin KW - Treatment effectiveness N2 - Sensory trick is an unusual clinical feature in cervical dystonia that attenuates disease symptoms by slight touch to a specific area of the face or head. Using a semi-quantitative questionnaire-based study of 197 patients with idiopathic cervical dystonia, we sought to determine probable pathophysiologic correlates, with the wider aim of examining its eventual clinical significance. The typical sensory trick, i.e., light touch, not necessitating the use of force leading to simple overpowering of dystonic activity, was present in 83 (42.1 %) patients. The vast majority of the patients required a specific sequence of sensorimotor inputs, including touch sensation on the face or different areas of the head, and also sensory and motor input of the hand itself. Deviations often led to a significant decrease in effectiveness and lack of expected benefit. Moreover, patients able to perform the maneuver reported compellingly higher subjective effect of botulinum toxin treatment (median 7 vs. 5 on a scale of 0–10; p\0.0001) and lower depression score (median 10 vs. 14 on the Montgomery Asberg Depression Rating scale; p\0.001). Overall, the results point to marked disruption of sensorimotor networks in cervical dystonia. The mechanism of the sensory trick action may be associated with balancing the abnormal activation patterns by specific sensorimotor inputs. Its presence may be considered a positive predictive factor for responsiveness to botulinum toxin treatment. ER -
FILIP, Pavel, Marek BALÁŽ, Rastislav ŠUMEC a Martin BAREŠ. The clinical phenomenology and associations of trick maneuvers in cervical dystonia. \textit{Journal of Neural Transmission}. Wien: Springer Wien, 2016, roč.~123, č.~3, s.~269-275. ISSN~0300-9564. Dostupné z: https://dx.doi.org/10.1007/s00702-015-1488-z.
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