| CONGUR, Gulsah, Medard PLUCNARA, Arzum ERDEM a Miroslav FOJTA. Detection of p53 Gene by Using Genomagnetic Assay Combined with Carbon Nanotube Modified Disposable Sensor Technology. Electroanalysis. WEINHEIM: WILEY-VCH Verlag GmbH, 2015, roč. 27, č. 7, s. 1579-1586. ISSN 1040-0397. doi:10.1002/elan.201400731. |
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@article{1322756,
author = {Congur, Gulsah and Plucnara, Medard and Erdem, Arzum and Fojta, Miroslav},
article_location = {WEINHEIM},
article_number = {7},
doi = {http://dx.doi.org/10.1002/elan.201400731},
keywords = {p53 Gene; Carbon nanotubes; Magnetic particles; DNA hybridization; Differential pulse voltammetry},
language = {eng},
issn = {1040-0397},
journal = {Electroanalysis},
title = {Detection of p53 Gene by Using Genomagnetic Assay Combined with Carbon Nanotube Modified Disposable Sensor Technology},
url = {http://onlinelibrary.wiley.com/doi/10.1002/elan.201400731/epdf},
volume = {27},
year = {2015}
}
TY - JOUR
ID - 1322756
AU - Congur, Gulsah - Plucnara, Medard - Erdem, Arzum - Fojta, Miroslav
PY - 2015
TI - Detection of p53 Gene by Using Genomagnetic Assay Combined with Carbon Nanotube Modified Disposable Sensor Technology
JF - Electroanalysis
VL - 27
IS - 7
SP - 1579-1586
EP - 1579-1586
PB - WILEY-VCH Verlag GmbH
SN - 10400397
KW - p53 Gene
KW - Carbon nanotubes
KW - Magnetic particles
KW - DNA hybridization
KW - Differential pulse voltammetry
UR - http://onlinelibrary.wiley.com/doi/10.1002/elan.201400731/epdf
L2 - http://onlinelibrary.wiley.com/doi/10.1002/elan.201400731/epdf
N2 - Electrochemical monitoring of DNA hybridization related to p53 gene sequence was investigated using genomagnetic assay combined with single walled carbon nanotube (SWCNT) modified pencil graphite electrodes (PGEs). The hybridization was performed either at magnetic beads (MB) surface or in solution. The enhanced guanine signal was obtained using SWCNT-PGEs compared to one obtained by unmodified PGEs. The selectivity of genomagnetic assay was tested under optimum conditions. The DLs were calculated as 0.88 mu M and 0.11 mu M for hybridization performed at MB surface and solution, respectively. This selective, practical and cost effective genomagnetic assay combined with SWCNT-PGEs is reported herein for the first time.
ER -
CONGUR, Gulsah, Medard PLUCNARA, Arzum ERDEM a Miroslav FOJTA. Detection of p53 Gene by Using Genomagnetic Assay Combined with Carbon Nanotube Modified Disposable Sensor Technology. \textit{Electroanalysis}. WEINHEIM: WILEY-VCH Verlag GmbH, 2015, roč.~27, č.~7, s.~1579-1586. ISSN~1040-0397. doi:10.1002/elan.201400731.
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