D 2015

Assessing progress of Parkinson's disease using acoustic analysis of phonation

MEKYSKA, J., Z. GALAZ, Z. MZOUREK, Z. SMÉKAL, Irena REKTOROVÁ et. al.

Basic information

Original name

Assessing progress of Parkinson's disease using acoustic analysis of phonation

Authors

MEKYSKA, J. (203 Czech Republic), Z. GALAZ (203 Czech Republic), Z. MZOUREK (203 Czech Republic), Z. SMÉKAL (203 Czech Republic), Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution), Ilona ELIÁŠOVÁ (203 Czech Republic, belonging to the institution), Milena KOŠŤÁLOVÁ (203 Czech Republic, belonging to the institution), Martina MRAČKOVÁ (203 Czech Republic, belonging to the institution), Dagmar BERÁNKOVÁ (203 Czech Republic, belonging to the institution), M. FAUNDEZ-ZANUY (724 Spain), K. LÓPEZ-DE- IPINA (724 Spain) and Jesus B. ALONSO-HERNANDEZ (724 Spain)

Edition

neuveden, 4th International Work Conference on Bio-Inspired Intelligence, IWOBI 2015, p. 111-118, 8 pp. 2015

Publisher

Institute of Electrical and Electronics Engineers Inc.

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Spain

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

printed version "print"

References:

RIV identification code

RIV/00216224:14740/15:00085829

Organization unit

Central European Institute of Technology

ISBN

978-1-4799-6174-0

Keywords in English

Biodiversity; Conservation; Decision trees; Intelligent systems; Neurodegenerative diseases; Patient rehabilitation; Speech Acoustic analysis;

Tags

International impact, Reviewed
Změněno: 11/1/2016 11:58, Martina Prášilová

Abstract

V originále

This paper deals with a complex acoustic analysis of phonation in patients with Parkinson's disease (PD) with a special focus on estimation of disease progress that is described by 7 different clinical scales (e. g. Unified Parkinson's disease rating scale or Beck depression inventory). The analysis is based on parametrization of 5 Czech vowels pronounced by 84 PD patients. Using classification and regression trees we estimated all clinical scores with maximal error lower or equal to 13 %. Best estimation was observed in the case of Mini-mental state examination (MAE = 0.77, estimation error 5.50 %). Finally, we proposed a binary classification based on random forests that is able to identify Parkinson's disease with sensitivity SEN = 92.86% (SPE = 85.71 %). The parametrization process was based on extraction of 107 speech features quantifying different clinical signs of hypokinetic dysarthria present in PD

Links

ED1.1.00/02.0068, research and development project
Name: CEITEC - central european institute of technology
NT13499, research and development project
Name: Řeč, její poruchy a kognitivní funkce u Parkinsonovy nemoci