KOK, Madeleine, Casper MIHL, Anna SEEHOFNEROVÁ, Jakub TUREK, Gregor JOST, Hubertus PIETSCH, Ulrike HABERLAND, Joachim E. WILDBERGER and Marco DAS. Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate. American Journal of Roentgenology. Reston: American Roentgen Ray Society, 2015, vol. 205, No 6, p. 1332-1338. ISSN 0361-803X. Available from: https://dx.doi.org/10.2214/AJR.14.13957.
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Basic information
Original name Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate
Authors KOK, Madeleine (528 Netherlands), Casper MIHL (528 Netherlands), Anna SEEHOFNEROVÁ (203 Czech Republic, belonging to the institution), Jakub TUREK (703 Slovakia, guarantor, belonging to the institution), Gregor JOST (276 Germany), Hubertus PIETSCH (276 Germany), Ulrike HABERLAND (276 Germany), Joachim E. WILDBERGER (528 Netherlands) and Marco DAS (528 Netherlands).
Edition American Journal of Roentgenology, Reston, American Roentgen Ray Society, 2015, 0361-803X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.660
RIV identification code RIV/00216224:14110/15:00086075
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.2214/AJR.14.13957
UT WoS 000365320400039
Keywords in English automated tube potential selection; contrast media; CT angiography; radiation exposure
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 20/1/2016 16:58.
Abstract
OBJECTIVE. The purpose of this study was to systematically investigate radiation dose reduction using automated tube voltage selection during CT angiography (CTA) and to evaluate the impact of contrast medium (CM) injection protocols on dose reduction. MATERIALS AND METHODS. A circulation phantom containing the thoracic and abdominal vasculature was used. Four different concentrations of CM (iopromide 300 and 370 mg I/mL and iomeprol 350 and 400 mg I/mL) were administered while maintaining an identical iodine delivery rate (1.8 g I/s) and total iodine load (20.0 g). Three different scanning protocols for CTA of the thoracoabdominal aorta were used: protocol A, no dose modulation; protocol B, automated tube current modulation (CARE Dose4D); and protocol C, automated tube voltage selection (CARE kV). The dose-length product was recorded to calculate the effective dose. Attenuation values (in Hounsfield units), image noise levels, and signal-to-noise ratios (SNRs) in six predefined intravascular sites (three thoracic and three abdominal) were measured by two readers. All values were analyzed using the Kruskal-Wallis test and two-way ANOVA. RESULTS. There was a significant reduction in the effective dose (in millisieverts) for protocols B (mean +/- SD, 2.03 +/- 0.1 mSv) and C (1.00 +/- 0.0 mSv) compared with protocol A (4.34 +/- 0.0 mSv). The dose was reduced by 53% for protocol B and by 77% for protocol C. No significant differences were found in the effective dose among the different CM injection protocols within the scanning protocols; all p values were > 0.05. The attenuation values and SNRs were comparable among all the different CM injection protocols; all p values were > 0.05. CONCLUSION. A large radiation dose reduction (77%) can be achieved using automated tube voltage selection independent of the CM injection protocol.
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