Determination of alkylphenols in water samples using liquid
chromatography-tandem mass spectrometry after pre-column
derivatization with dansyl chloride

J 2015

Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride

PERNICA, Marek, Petra POLOUCKÁ, Marta SEIFERTOVÁ and Zdeněk ŠIMEK

Basic information

Original name

Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride

Name in Czech

Stanovení alkylfenolů ve vzorcích vody pomocí kapalinové chromatografie a tandemové hmotnostní spektrometrie po předkolonové derivatizaci dansyl chloridem

Authors

PERNICA, Marek (203 Czech Republic, belonging to the institution), Petra POLOUCKÁ (203 Czech Republic, belonging to the institution), Marta SEIFERTOVÁ (203 Czech Republic, belonging to the institution) and Zdeněk ŠIMEK (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Chromatography A, AMSTERDAM (NETHERLANDS), Elsevier, 2015, 0021-9673

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10406 Analytical chemistry

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.926

RIV identification code

RIV/00216224:14310/15:00081546

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1016/j.chroma.2015.09.030

UT WoS

000363080700006

Keywords in English

Alkylphenols; Liquid chromatography; Electrospray ionization; Tandem mass spectrometry; Chemical derivatization of alkylphenols

Abstract

V originále

The present study describes an effect of reaction condition of pre-column derivatization of alkylphenols (APs): bisphenol A (BPA), 4-tert-octylphenol (4-t-OP), 4-octylphenol (4-OP), 4-n-nonylphenol (4-n-NP), and isomers of 4-nonylphenol (iso-NP) with 5-(dimethylamino) naphthalene-1-sulfonyl chloride (dansyl chloride, DNSC) on their LC–ESI–MS/MS determination in water samples. Chemical derivatization improves the sensitivity and selectivity of LC–MS/MS analysis. In principle, alkylphenols can be analyzed by LC–MS/MS without derivatization. However, pre-column derivatization of APs increases the sensitivity up to 1000 times in comparison with the analysis of underivatized alkylphenols. Reaction conditions affecting formation of the DNSC-derivatives, such as various solvent, reaction temperature, reaction time, DNSC concentration and pH values were tested.

Links

GA13-20357S, research and development project

Name: Studium distribuce steroidních látek ve složkách pevných environmentálních matric.

Investor: Czech Science Foundation

LM2011028, research and development project

Name: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí

Investor: Ministry of Education, Youth and Sports of the CR

LO1214, research and development project

Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

PERNICA, Marek, Petra POLOUCKÁ, Marta SEIFERTOVÁ and Zdeněk ŠIMEK. Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride. Journal of Chromatography A. AMSTERDAM (NETHERLANDS): Elsevier, 2015, vol. 1417, OCTOBER, p. 49-56. ISSN 0021-9673. Available from: https://dx.doi.org/10.1016/j.chroma.2015.09.030.

@article{1333884,
   author = {Pernica, Marek and Poloucká, Petra and Seifertová, Marta and Šimek, Zdeněk},
   article_location = {AMSTERDAM (NETHERLANDS)},
   article_number = {OCTOBER},
   doi = {http://dx.doi.org/10.1016/j.chroma.2015.09.030},
   keywords = {Alkylphenols; Liquid chromatography; Electrospray ionization; Tandem mass spectrometry; Chemical derivatization of alkylphenols},
   language = {eng},
   issn = {0021-9673},
   journal = {Journal of Chromatography A},
   title = {Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride},
   url = {http://www.sciencedirect.com/science/article/pii/S002196731501314X},
   volume = {1417},
   year = {2015}
}

TY  - JOUR
ID  - 1333884
AU  - Pernica, Marek - Poloucká, Petra - Seifertová, Marta - Šimek, Zdeněk
PY  - 2015
TI  - Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride
JF  - Journal of Chromatography A
VL  - 1417
IS  - OCTOBER
SP  - 49-56
EP  - 49-56
PB  - Elsevier
SN  - 00219673
KW  - Alkylphenols
KW  - Liquid chromatography
KW  - Electrospray ionization
KW  - Tandem mass spectrometry
KW  - Chemical derivatization of alkylphenols
UR  - http://www.sciencedirect.com/science/article/pii/S002196731501314X
L2  - http://www.sciencedirect.com/science/article/pii/S002196731501314X
N2  - The present study describes an effect of reaction condition of pre-column derivatization of alkylphenols (APs): bisphenol A (BPA), 4-tert-octylphenol (4-t-OP), 4-octylphenol (4-OP), 4-n-nonylphenol (4-n-NP), and isomers of 4-nonylphenol (iso-NP) with 5-(dimethylamino) naphthalene-1-sulfonyl chloride (dansyl chloride, DNSC) on their LC–ESI–MS/MS determination in water samples. Chemical derivatization improves the sensitivity and selectivity of LC–MS/MS analysis. In principle, alkylphenols can be analyzed by LC–MS/MS without derivatization. However, pre-column derivatization of APs increases the sensitivity up to 1000 times in comparison with the analysis of underivatized alkylphenols. Reaction conditions affecting formation of the DNSC-derivatives, such as various solvent, reaction temperature, reaction time, DNSC concentration and pH values were tested.
ER  -

PERNICA, Marek, Petra POLOUCKÁ, Marta SEIFERTOVÁ and Zdeněk ŠIMEK. Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride. \textit{Journal of Chromatography A}. AMSTERDAM (NETHERLANDS): Elsevier, 2015, vol.~1417, OCTOBER, p.~49-56. ISSN~0021-9673. Available from: https://dx.doi.org/10.1016/j.chroma.2015.09.030.

Detailed Information on Publication Record