Determination of alkylphenols in water samples using liquid
chromatography-tandem mass spectrometry after pre-column
derivatization with dansyl chloride

J 2015

Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride

PERNICA, Marek; Petra POLOUCKÁ; Marta SEIFERTOVÁ and Zdeněk ŠIMEK

Basic information

Original name

Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride

Name in Czech

Stanovení alkylfenolů ve vzorcích vody pomocí kapalinové chromatografie a tandemové hmotnostní spektrometrie po předkolonové derivatizaci dansyl chloridem

Authors

PERNICA, Marek (203 Czech Republic, belonging to the institution); Petra POLOUCKÁ (203 Czech Republic, belonging to the institution); Marta SEIFERTOVÁ (203 Czech Republic, belonging to the institution) and Zdeněk ŠIMEK (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Chromatography A, AMSTERDAM (NETHERLANDS), Elsevier, 2015, 0021-9673

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10406 Analytical chemistry

Country of publisher

Netherlands

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Impact factor

Impact factor: 3.926

RIV identification code

RIV/00216224:14310/15:00081546

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1016/j.chroma.2015.09.030

UT WoS

000363080700006

EID Scopus

2-s2.0-84943450603

Keywords in English

Alkylphenols; Liquid chromatography; Electrospray ionization; Tandem mass spectrometry; Chemical derivatization of alkylphenols

Abstract

V originále

The present study describes an effect of reaction condition of pre-column derivatization of alkylphenols (APs): bisphenol A (BPA), 4-tert-octylphenol (4-t-OP), 4-octylphenol (4-OP), 4-n-nonylphenol (4-n-NP), and isomers of 4-nonylphenol (iso-NP) with 5-(dimethylamino) naphthalene-1-sulfonyl chloride (dansyl chloride, DNSC) on their LC–ESI–MS/MS determination in water samples. Chemical derivatization improves the sensitivity and selectivity of LC–MS/MS analysis. In principle, alkylphenols can be analyzed by LC–MS/MS without derivatization. However, pre-column derivatization of APs increases the sensitivity up to 1000 times in comparison with the analysis of underivatized alkylphenols. Reaction conditions affecting formation of the DNSC-derivatives, such as various solvent, reaction temperature, reaction time, DNSC concentration and pH values were tested.

Links

GA13-20357S, research and development project

Name: Studium distribuce steroidních látek ve složkách pevných environmentálních matric.

Investor: Czech Science Foundation

LM2011028, research and development project

Name: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí

Investor: Ministry of Education, Youth and Sports of the CR

LO1214, research and development project

Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX)

Investor: Ministry of Education, Youth and Sports of the CR

Cite

PERNICA, Marek; Petra POLOUCKÁ; Marta SEIFERTOVÁ and Zdeněk ŠIMEK. Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride. Journal of Chromatography A. AMSTERDAM (NETHERLANDS): Elsevier, 2015, vol. 1417, OCTOBER, p. 49-56. ISSN 0021-9673. Available from: https://dx.doi.org/10.1016/j.chroma.2015.09.030.

@article{1333884,
   author = {Pernica, Marek and Poloucká, Petra and Seifertová, Marta and Šimek, Zdeněk},
   article_location = {AMSTERDAM (NETHERLANDS)},
   article_number = {OCTOBER},
   doi = {http://dx.doi.org/10.1016/j.chroma.2015.09.030},
   keywords = {Alkylphenols; Liquid chromatography; Electrospray ionization; Tandem mass spectrometry; Chemical derivatization of alkylphenols},
   language = {eng},
   issn = {0021-9673},
   journal = {Journal of Chromatography A},
   title = {Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride},
   url = {http://www.sciencedirect.com/science/article/pii/S002196731501314X},
   volume = {1417},
   year = {2015}
}

TY  - JOUR
ID  - 1333884
AU  - Pernica, Marek - Poloucká, Petra - Seifertová, Marta - Šimek, Zdeněk
PY  - 2015
TI  - Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride
JF  - Journal of Chromatography A
VL  - 1417
IS  - OCTOBER
SP  - 49-56
EP  - 49-56
PB  - Elsevier
SN  - 00219673
KW  - Alkylphenols
KW  - Liquid chromatography
KW  - Electrospray ionization
KW  - Tandem mass spectrometry
KW  - Chemical derivatization of alkylphenols
UR  - http://www.sciencedirect.com/science/article/pii/S002196731501314X
L2  - http://www.sciencedirect.com/science/article/pii/S002196731501314X
N2  - The present study describes an effect of reaction condition of pre-column derivatization of alkylphenols (APs): bisphenol A (BPA), 4-tert-octylphenol (4-t-OP), 4-octylphenol (4-OP), 4-n-nonylphenol (4-n-NP), and isomers of 4-nonylphenol (iso-NP) with 5-(dimethylamino) naphthalene-1-sulfonyl chloride (dansyl chloride, DNSC) on their LC–ESI–MS/MS determination in water samples. Chemical derivatization improves the sensitivity and selectivity of LC–MS/MS analysis. In principle, alkylphenols can be analyzed by LC–MS/MS without derivatization. However, pre-column derivatization of APs increases the sensitivity up to 1000 times in comparison with the analysis of underivatized alkylphenols. Reaction conditions affecting formation of the DNSC-derivatives, such as various solvent, reaction temperature, reaction time, DNSC concentration and pH values were tested.
ER  -

PERNICA, Marek; Petra POLOUCKÁ; Marta SEIFERTOVÁ and Zdeněk ŠIMEK. Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride. \textit{Journal of Chromatography A}. AMSTERDAM (NETHERLANDS): Elsevier, 2015, vol.~1417, OCTOBER, p.~49-56. ISSN~0021-9673. Available from: https://dx.doi.org/10.1016/j.chroma.2015.09.030.

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