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@article{1334016,
author = {Hendrych, Michal and Olejníčková, Veronika and Nováková, Marie},
article_location = {Bratislava},
article_number = {1},
keywords = {strontium; calcium; cardiomyocyte; sarcoplasmatic reticulum; mitochondria},
language = {eng},
issn = {0231-5882},
journal = {General Physiology and Biophysics},
title = {Calcium versus strontium handling by the heart muscle},
volume = {35},
year = {2016}
}
TY - JOUR
ID - 1334016
AU - Hendrych, Michal - Olejníčková, Veronika - Nováková, Marie
PY - 2016
TI - Calcium versus strontium handling by the heart muscle
JF - General Physiology and Biophysics
VL - 35
IS - 1
SP - 13-23
EP - 13-23
PB - Slovak Academy of Sciences
SN - 02315882
KW - strontium
KW - calcium
KW - cardiomyocyte
KW - sarcoplasmatic reticulum
KW - mitochondria
N2 - Calcium plays a crucial role in numerous processes in living systems, from both intracellular and intercellular signalling to blood clotting. Calcium can be replaced by strontium in various intracellular processes due to high level of their similarity and strontium thus may serve as a valuable tool for different experimental studies. On the other hand, strontium is also used in clinical medicine and is commonly taken to the human body with food and water. The negative cardiac side effects of strontium therapy of osteoporosis and bone metastases are well known, but still not fully explained. This fact explains enhanced interest in this element and its impact on human body. This article reviews effects of calcium and strontium on several biochemical and physiological processes, with special emphasis on cardiac muscle.
ER -
HENDRYCH, Michal, Veronika OLEJNÍČKOVÁ a Marie NOVÁKOVÁ. Calcium versus strontium handling by the heart muscle. \textit{General Physiology and Biophysics}. Bratislava: Slovak Academy of Sciences, roč.~35, č.~1, s.~13-23. ISSN~0231-5882. 2016.
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