1,3-Dipolar Cycloaddition in the Preparation of New Fused Heterocyclic Compounds via Thermal Initiation

PORUBSKÝ, Martin, Lukáš TENORA and Milan POTÁČEK. 1,3-Dipolar Cycloaddition in the Preparation of New Fused Heterocyclic Compounds via Thermal Initiation. Molecules. Mayer und Muller, 2016, vol. 21, No 2, p. "nestrankovano", 11 pp. ISSN 1420-3049. Available from: https://dx.doi.org/10.3390/molecules21020187.

Basic information

Original name

1,3-Dipolar Cycloaddition in the Preparation of New Fused Heterocyclic Compounds via Thermal Initiation

Authors

PORUBSKÝ, Martin (703 Slovakia, belonging to the institution), Lukáš TENORA (203 Czech Republic, belonging to the institution) and Milan POTÁČEK (203 Czech Republic, guarantor, belonging to the institution)

Edition

Molecules, Mayer und Muller, 2016, 1420-3049

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10401 Organic chemistry

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.861

RIV identification code

RIV/00216224:14310/16:00089342

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.3390/molecules21020187

UT WoS

000371895900111

Keywords in English

1 3 dipolar cycloaddition; fused heterocycles; thermal initiation; 3 aminobenzo[b]furan 2 carbaldehyde

Tags

AKR, rivok

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Abstract

V originále

This paper describes the synthesis of precursors with a benzo[b]furan skeleton for the intramolecular 1,3-dipolar cycloaddition of azomethine ylides prepared from N-substituted 3-allyl-aminobenzo[b]furan-2-aldehydes and secondary amines derived from alfa-amino acid esters. Reactions were initiated by heating. The products consisted of four fused rings with three stereogenic centers. Their structure and stereochemistry were determined by NMR spectra and X-ray measurements.