J 2016

Urinary stones as a novel matrix for human biomonitoring of toxic and essential elements

KUTA, Jan, Soňa SMETANOVÁ, Daniela BENOVÁ, Tamara KOŘISTKOVÁ, Jiří MACHÁT et. al.

Basic information

Original name

Urinary stones as a novel matrix for human biomonitoring of toxic and essential elements

Authors

KUTA, Jan (203 Czech Republic, guarantor, belonging to the institution), Soňa SMETANOVÁ (203 Czech Republic, belonging to the institution), Daniela BENOVÁ (703 Slovakia, belonging to the institution), Tamara KOŘISTKOVÁ (203 Czech Republic) and Jiří MACHÁT (203 Czech Republic, belonging to the institution)

Edition

ENVIRONMENTAL GEOCHEMISTRY AND HEALTH, DORDRECHT, SPRINGER, 2016, 0269-4042

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.616

RIV identification code

RIV/00216224:14310/16:00089412

Organization unit

Faculty of Science

UT WoS

000368685100011

Keywords in English

Urinary stones; Trace elements; Biomonitoring; Exposure; Urolithiasis

Tags

Tags

International impact, Reviewed
Změněno: 31/1/2017 09:17, Mgr. Michaela Hylsová, Ph.D.

Abstract

V originále

Monitoring of body burden of toxic elements is usually based on analysis of concentration of particular elements in blood, urine and/or hair. Analysis of these matrices, however, predominantly reflects short- or medium-term exposure to trace elements or pollutants. In this work, urinary stones were investigated as a matrix for monitoring long-term exposure to toxic and essential elements. A total of 431 samples of urinary calculi were subjected to mineralogical and elemental analysis by infrared spectroscopy and inductively coupled plasma mass spectrometry. The effect of mineralogical composition of the stones and other parameters such as sex, age and geographical location on contents of trace and minor elements is presented. Our results demonstrate the applicability of such approach and confirm that the analysis of urinary calculi can be helpful in providing complementary information on human exposure to trace metals and their excretion. Analysis of whewellite stones (calcium oxalate monohydrate) with content of phosphorus < 0.6 % has been proved to be a promising tool for biomonitoring of trace and minor elements.

Links

LM2011028, research and development project
Name: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí
Investor: Ministry of Education, Youth and Sports of the CR
LO1214, research and development project
Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX)
Investor: Ministry of Education, Youth and Sports of the CR