Stem Cell Differentiation on Conducting Polyaniline

J 2015

Stem Cell Differentiation on Conducting Polyaniline

HUMPOLÍČEK, Petr, Katarzyna Anna RADASZKIEWICZ, Věra KAŠPÁRKOVÁ, Jaroslav STEJSKAL, Miroslava TRCHOVÁ et. al.

Basic information

Original name

Stem Cell Differentiation on Conducting Polyaniline

Authors

HUMPOLÍČEK, Petr (203 Czech Republic, guarantor), Katarzyna Anna RADASZKIEWICZ (616 Poland, belonging to the institution), Věra KAŠPÁRKOVÁ (203 Czech Republic), Jaroslav STEJSKAL (203 Czech Republic), Miroslava TRCHOVÁ (203 Czech Republic), Zdenka KUCEKOVÁ (203 Czech Republic), Hana VIČAROVÁ (203 Czech Republic, belonging to the institution), Jiří PACHERNÍK (203 Czech Republic, belonging to the institution), Marián LEHOCKÝ (703 Slovakia) and Antonín MINAŘÍK (203 Czech Republic)

Edition

RSC Advances, Cambridge, Royal Society of Chemistry, 2015, 2046-2069

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10404 Polymer science

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.289

RIV identification code

RIV/00216224:14310/15:00087513

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1039/C5RA12218J

UT WoS

000359568400070

Keywords (in Czech)

Polyanilin; kmenove buňky

Keywords in English

Polyaniline; stem cells

Abstract

V originále

Polyaniline is a promising conducting polymer with broad application potential in biomedicine. Its medical use, however, requires both biocompatibility and suitable physico-chemical and surface properties. The microstructure, electrical properties, and surface characteristics of polyaniline salt, polyaniline base, and polyaniline deposited with biologically active poly(2-acrylamido-2-methyl-1-propanesulfonic acid) were revealed using atomic force microscopy, contact angle measurements, and Raman spectroscopy. As conducting polymers can be preferentially applied in tissue engineering of heart and nervous tissues, the cardiomyogenesis in pure cardiomyocytes derived from embryonic stem cells and neurogenesis in neural progenitors isolated from embryonal 13 dpc brain were further investigated. The results show that neither cardiomyogenesis nor neurogenesis were influenced by any of the tested polyaniline films. However, the most favorable cell behaviour was observed on pristine polyaniline base; therefore, polyaniline in pristine forms without any further modification can be applied in a variety of biomedical fields.

Citovat

HUMPOLÍČEK, Petr, Katarzyna Anna RADASZKIEWICZ, Věra KAŠPÁRKOVÁ, Jaroslav STEJSKAL, Miroslava TRCHOVÁ, Zdenka KUCEKOVÁ, Hana VIČAROVÁ, Jiří PACHERNÍK, Marián LEHOCKÝ and Antonín MINAŘÍK. Stem Cell Differentiation on Conducting Polyaniline. RSC Advances. Cambridge: Royal Society of Chemistry, 2015, vol. 5, No 84, p. 68796-68805. ISSN 2046-2069. Available from: https://dx.doi.org/10.1039/C5RA12218J.

@article{1338723,
   author = {Humpolíček, Petr and Radaszkiewicz, Katarzyna Anna and Kašpárková, Věra and Stejskal, Jaroslav and Trchová, Miroslava and Kuceková, Zdenka and Vičarová, Hana and Pacherník, Jiří and Lehocký, Marián and Minařík, Antonín},
   article_location = {Cambridge},
   article_number = {84},
   doi = {http://dx.doi.org/10.1039/C5RA12218J},
   keywords = {Polyaniline; stem cells},
   language = {eng},
   issn = {2046-2069},
   journal = {RSC Advances},
   title = {Stem Cell Differentiation on Conducting Polyaniline},
   url = {http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C5RA12218J#!divAbstract},
   volume = {5},
   year = {2015}
}

TY  - JOUR
ID  - 1338723
AU  - Humpolíček, Petr - Radaszkiewicz, Katarzyna Anna - Kašpárková, Věra - Stejskal, Jaroslav - Trchová, Miroslava - Kuceková, Zdenka - Vičarová, Hana - Pacherník, Jiří - Lehocký, Marián - Minařík, Antonín
PY  - 2015
TI  - Stem Cell Differentiation on Conducting Polyaniline
JF  - RSC Advances
VL  - 5
IS  - 84
SP  - 68796-68805
EP  - 68796-68805
PB  - Royal Society of Chemistry
SN  - 20462069
KW  - Polyaniline
KW  - stem cells
UR  - http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C5RA12218J#!divAbstract
L2  - http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C5RA12218J#!divAbstract
N2  - Polyaniline is a promising conducting polymer with broad application potential in biomedicine. Its medical use, however, requires both biocompatibility and suitable physico-chemical and surface properties. The microstructure, electrical properties, and surface characteristics of polyaniline salt, polyaniline base, and polyaniline deposited with biologically active poly(2-acrylamido-2-methyl-1-propanesulfonic acid) were revealed using atomic force microscopy, contact angle measurements, and Raman spectroscopy. As conducting polymers can be preferentially applied in tissue engineering of heart and nervous tissues, the cardiomyogenesis in pure cardiomyocytes derived from embryonic stem cells and neurogenesis in neural progenitors isolated from embryonal 13 dpc brain were further investigated. The results show that neither cardiomyogenesis nor neurogenesis were influenced by any of the tested polyaniline films. However, the most favorable cell behaviour was observed on pristine polyaniline base; therefore, polyaniline in pristine forms without any further modification can be applied in a variety of biomedical fields.
ER  -

HUMPOLÍČEK, Petr, Katarzyna Anna RADASZKIEWICZ, Věra KAŠPÁRKOVÁ, Jaroslav STEJSKAL, Miroslava TRCHOVÁ, Zdenka KUCEKOVÁ, Hana VIČAROVÁ, Jiří PACHERNÍK, Marián LEHOCKÝ and Antonín MINAŘÍK. Stem Cell Differentiation on Conducting Polyaniline. \textit{RSC Advances}. Cambridge: Royal Society of Chemistry, 2015, vol.~5, No~84, p.~68796-68805. ISSN~2046-2069. Available from: https://dx.doi.org/10.1039/C5RA12218J.

Detailed Information on Publication Record