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@proceedings{1339630,
author = {Jančaříková, Gita and Demo, Gabriel and Komárek, Jan and Wimmerová, Michaela},
booktitle = {XVI. Setkání biochemiků a molekulárních biologů},
keywords = {lectin, Photorhabdus asymbiotica, Structure-functional studies},
language = {eng},
isbn = {978-80-210-7340-1},
title = {Newly identified lectin from Photorhabdus asymbiotica and its structure-functional study},
year = {2014}
}
TY - CONF
ID - 1339630
AU - Jančaříková, Gita - Demo, Gabriel - Komárek, Jan - Wimmerová, Michaela
PY - 2014
TI - Newly identified lectin from Photorhabdus asymbiotica and its structure-functional study
SN - 9788021073401
KW - lectin, Photorhabdus asymbiotica, Structure-functional studies
N2 - Our project is focused on study of a new lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs to the Photorabdus genus together with Photorabdus luminiscens and Photorabdus temperata. The latter 2 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome with the predicted structure similarity to the lectins from so-called AAL family, which are specific for fucosylated oligosaccharide. The AAL family contains AAL from Aleuria aurantia which inhibits a repair of epithelia or the RSL lectin from Ralstonia solanaccearum predicted as one of the key virulent factors of this plant pathogen.
ER -
JANČAŘÍKOVÁ, Gita, Gabriel DEMO, Jan KOMÁREK and Michaela WIMMEROVÁ. Newly identified lectin from Photorhabdus asymbiotica and its structure-functional study. In \textit{XVI. Setkání biochemiků a molekulárních biologů}. 2014. ISBN~978-80-210-7340-1.
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