JANČAŘÍKOVÁ, Gita, Gabriel DEMO, Jan KOMÁREK and Michaela WIMMEROVÁ. Study of PHL lectin from Photorabdus asymbiotica to revealing its role in pathogenesis. In XVII. setkání biochemiků a molekulárních biologů. 2015. ISBN 978-80-210-8015-7.
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Basic information
Original name Study of PHL lectin from Photorabdus asymbiotica to revealing its role in pathogenesis
Authors JANČAŘÍKOVÁ, Gita (203 Czech Republic, belonging to the institution), Gabriel DEMO (703 Slovakia, belonging to the institution), Jan KOMÁREK (203 Czech Republic, belonging to the institution) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition XVII. setkání biochemiků a molekulárních biologů, 2015.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10600 1.6 Biological sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14740/15:00087852
Organization unit Central European Institute of Technology
ISBN 978-80-210-8015-7
Keywords (in Czech) Lektin;Phothorabdus asymbiotica; strukturně-funkční studie
Keywords in English lectin;Photorhabdus asymbiotica;Structure-functional studies
Changed by Changed by: Mgr. Eva Špillingová, učo 110713. Changed: 27/4/2017 13:18.
Abstract
Proteins and glycoproteins, which specifically recognize and reversibly bind glycoconjugates, form a very important group called lectins. Lectins play a crucial role in many physiological and pathophysiological processes including immunological reactions or interactions between tissue’s cells. Besides these functions they also play a very important role in interactions between a pathogen and its host - they can mediate the first step of an expansion of infection. Currently, lectins become essential tools in the biological and medical research, i.e. to follow agglutination of erythrocytes, detection and characterization of different saccharide composition of glycoconjugates, mitogenic stimulation of lymphocytes, inhibition of fungal, bacterial and viral growth, etc.
Links
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
GA13-25401S, research and development projectName: Studium proteinů z patogenů zapojených do rozpoznávání hostitelského organismu
Investor: Czech Science Foundation
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