a 2015

Study of PHL lectin from Photorabdus asymbiotica to revealing its role in pathogenesis

JANČAŘÍKOVÁ, Gita, Gabriel DEMO, Jan KOMÁREK and Michaela WIMMEROVÁ

Basic information

Original name

Study of PHL lectin from Photorabdus asymbiotica to revealing its role in pathogenesis

Authors

JANČAŘÍKOVÁ, Gita (203 Czech Republic, belonging to the institution), Gabriel DEMO (703 Slovakia, belonging to the institution), Jan KOMÁREK (203 Czech Republic, belonging to the institution) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

XVII. setkání biochemiků a molekulárních biologů, 2015

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14740/15:00087852

Organization unit

Central European Institute of Technology

ISBN

978-80-210-8015-7

Keywords (in Czech)

Lektin;Phothorabdus asymbiotica; strukturně-funkční studie

Keywords in English

lectin;Photorhabdus asymbiotica;Structure-functional studies
Změněno: 27/4/2017 13:18, Mgr. Eva Špillingová

Abstract

V originále

Proteins and glycoproteins, which specifically recognize and reversibly bind glycoconjugates, form a very important group called lectins. Lectins play a crucial role in many physiological and pathophysiological processes including immunological reactions or interactions between tissue’s cells. Besides these functions they also play a very important role in interactions between a pathogen and its host - they can mediate the first step of an expansion of infection. Currently, lectins become essential tools in the biological and medical research, i.e. to follow agglutination of erythrocytes, detection and characterization of different saccharide composition of glycoconjugates, mitogenic stimulation of lymphocytes, inhibition of fungal, bacterial and viral growth, etc.

Links

ED1.1.00/02.0068, research and development project
Name: CEITEC - central european institute of technology
GA13-25401S, research and development project
Name: Studium proteinů z patogenů zapojených do rozpoznávání hostitelského organismu
Investor: Czech Science Foundation