SAMPSON, Joshua N., William A. WHEELER, Meredith YEAGER, Orestis PANAGIOTOU, Zhaoming WANG, Sonja I. BERNDT, Qing LAN, Christian C. ABNET, Laufey T. AMUNDADOTTIR, Jonine D. FIGUEROA, Maria Teresa LANDI, Lisa MIRABELLO, Sharon A. SAVAGE, Philip R. TAYLOR, Immaculata DEVIVO, Katherine A. MCGLYNN, Mark P. PURDUE, Preetha RAJARAMAN, Hans-Olov ADAMI, Anders AHLBOM, Demetrius ALBANES, Maria Fernanda AMARY, She-Juan AN, Ulrika ANDERSSON, Gerald Jr. ANDRIOLE, Irene L. ANDRULIS, Emanuele ANGELUCCI, Stephen M. ANSELL, Cecilia ARICI, Bruce K. ARMSTRONG, Alan A. ARSLAN, Melissa A. AUSTIN, Dalsu BARIS, Donald A. BARKAUSKAS, Bryan A. BASSIG, Nikolaus BECKER, Yolanda BENAVENTE, Simone BENHAMOU, Christine BERG, David VAN DEN BERG, Leslie BERNSTEIN, Kimberly A. BERTRAND, Brenda M. BIRMANN, Amanda BLACK, Heiner BOEING, Paolo BOFFETTA, Marie-Christine BOUTRON-RUAULT, Paige M. BRACCI, Louise BRINTON, Angela R. BROOKS-WILSON, H. Bas BUENO-DE-MESQUITA, Laurie BURDETT, Julie BURING, Mary Ann BUTLER, Qiuyin CAI, Geraldine CANCEL-TASSIN, Federico CANZIAN, Alfredo CARRATO, Tania CARREON, Angela CARTA, John K.C. CHAN, Ellen T. CHANG, Gee-Chen CHANG, I-Shou CHANG, Jiang CHANG, Jenny CHANG-CLAUDE, Chien-Jen CHEN, Chin-Yi CHEN, Chu CHEN, Chung-Hsing CHEN, Constance CHEN, Hongyan CHEN, Kexin CHEN, Kuan-Yu CHEN, Kun-Chieh CHEN, Ying CHEN, Ying-Hsiang CHEN, Yi-Song CHEN, Yuh-Min CHEN, Li-Hsin CHIEN, Maria-Dolores CHIRLAQUE, Jin Eun CHOI, Yi Young CHOI, Wong-Ho CHOW, Charles C. CHUNG, Jacqueline CLAVEL, Franoise CLAVEL-CHAPELON, Pierluigi COCCO, Joanne S. COLT, Eva COMPERAT, Lucia CONDE, Joseph M. CONNORS, David CONTI, Victoria K. CORTESSIS, Michelle COTTERCHIO, Wendy COZEN, Simon CROUCH, Marta CROUS-BOU, Olivier CUSSENOT, Faith G. DAVIS, Ti DING, W. Ryan DIVER, Miren DORRONSORO, Laure DOSSUS, Eric J. DUELL, Maria Grazia ENNAS, Ralph L. ERICKSON, Maria FEYCHTING, Adrienne M. FLANAGAN, Lenka FORETOVÁ, Joseph F. Jr. FRAUMENI, Neal D. FREEDMAN, Laura E. Beane FREEMAN, Charles FUCHS, Manuela GAGO-DOMINGUEZ, Steven GALLINGER, Yu-Tang GAO, Susan M. GAPSTUR, Montserrat GARCIA-CLOSAS, Reina GARCIA-CLOSAS, Randy D. GASCOYNE, Julie GASTIER-FOSTER, Mia M. GAUDET, J. Michael GAZIANO, Carol GIFFEN, Graham G. GILES, Edward GIOVANNUCCI, Bengt GLIMELIUS, Michael GOGGINS, Nalan GOKGOZ, Alisa M. GOLDSTEIN, Richard GORLICK, Myron GROSS, Robert III GRUBB, Jian GU, Peng GUAN, Marc GUNTER, Huan GUO, Thomas M. HABERMANN, Christopher A. HAIMAN, Dina HALAI, Goran HALLMANS, Manal HASSAN, Claudia HATTINGER, Qincheng HE, Xingzhou HE, Kathy HELZLSOUER, Brian HENDERSON, Roger HENRIKSSON, Henrik HJALGRIM, Judith HOFFMAN-BOLTON, Chancellor HOHENSEE, Theodore R. HOLFORD, Elizabeth A. HOLLY, Yun-Chul HONG, Robert N. HOOVER, Pamela L. HORN-ROSS, G.M. Monawar HOSAIN, H. Dean HOSGOOD, Chin-Fu HSIAO, Nan HU, Wei HU, Zhibin HU, Ming-Shyan HUANG, Jose-Maria HUERTA, Jen-Yu HUNG, Amy HUTCHINSON, Peter D. INSKIP, Rebecca D. JACKSON, Eric J. JACOBS, Mazda JENAB, Hyo-Sung JEON, Bu-Tian JI, Guangfu JIN, Li JIN, Christoffer JOHANSEN, Alison JOHNSON, Yoo Jin JUNG, Rudolph KAAKS, Aruna KAMINENI, Eleanor KANE, Cang Hyan KANG, Margaret R. KARAGAS, Rachel S. KELLY, Kay-Tee KHAW, Christopher KIM, Hee Nam KIM, Jin Hee KIM, Jun Suk KIM, Yeul Hong KIM, Young Tae KIM, Young Chul KIM, Cari M. KITAHARA, Alison P. KLEIN, Robert J. KLEIN, Manolis KOGEVINAS, Takashi KOHNO, Laurence N. KOLONEL, Charles KOOPERBERG, Anne KRICKER, Vittorio KROGH, Hideo KUNITOH, Robert C. KURTZ, Sun-Seog KWEON, Andrea LACROIX, Charles LAWRENCE, Fernando LECANDA, Victor Ho Fun LEE, Donghui LI, Haixin LI, Jihua LI, Yao-Jen LI, Yyqing LI, Linda M. LIAO, Mark LIEBOW, Tracy LIGHTFOOT, Wei-Yen LIM, Chien-Chung LIN, Dongxin LIN, Sasa LINDSTROM, Martha S. LINET, Brian K. LINK, Chenwei LIU, Jianjun LIU, Li LIU, Boerje LJUNGBERG, Josep LLORETA, Simonetta DI LOLLO, Daru LU, Eiluv LUND, Nuria MALATS, Satu MANNISTO, Loic LE MARCHAND, Neyssa MARINA, Giovanna MASALA, Giuseppe MASTRANGELO, Keitaro MATSUO, Marc MAYNADIE, James MCKAY, Roberta MCKEAN-COWDIN, Mads MELBYE, Beatrice S. MELIN, Dominique S. MICHAUD, Tetsuya MITSUDOMI, Alain MONNEREAU, Rebecca MONTALVAN, Lee E. MOORE, Lotte Maxild MORTENSEN, Alexandra NIETERS, Kari E. NORTH, Anne J. NOVAK, Ann L. OBERG, Kenneth OFFIT, In-Jae OH, Sara H. OLSON, Domenico PALLI, William PAO, In Kyu PARK, Jae Yong PARK, Kyong Hwa PARK, Ana PATINO-GARCIA, Sofia PAVANELLO, Petra H.M. PEETERS, Reury-Perng PERNG, Ulrike PETERS, Gloria M. PETERSEN, Piero PICCI, Malcolm C. PIKE, Stefano PORRU, Jennifer PRESCOTT, Ludmila PROKUNINA-OLSSON, Biyun QIAN, You-Lin QIAO, Marco RAIS, Elio RIBOLI, Jacques RIBY, Harvey A. RISCH, Cosmeri RIZZATO, Rebecca RODABOUGH, Eve ROMAN, Morgan ROUPRET, Avima M. RUDER, Silvia de SANJOSE, Ghislaine SCELO, Alan SCHNED, Fredrick SCHUMACHER, Kendra SCHWARTZ, Molly SCHWENN, Katia SCOTLANDI, Adeline SEOW, Consol SERRA, Massimo SERRA, Howard D. SESSO, Veronica Wendy SETIAWAN, Gianluca SEVERI, Richard K. SEVERSON, Tait D. SHANAFELT, Hongbing SHEN, Wei SHEN, Min-Ho SHIN, Kouya SHIRAISHI, Xiao-Ou SHU, Afshan SIDDIQ, Luis SIERRASESUMAGA, Alan Dart Loon SIHOE, Christine F. SKIBOLA, Alex SMITH, Martyn T. SMITH, Melissa C. SOUTHEY, John J. SPINELLI, Anthony STAINES, Meir STAMPFER, Marianna C. STERN, Victoria L. STEVENS, Rachael S. STOLZENBERG-SOLOMON, Jian SU, Wu-Chou SU, Malin SUND, Jae Sook SUNG, Sook Whan SUNG, Wen TAN, Wei TANG, Adonina TARDON, David THOMAS, Carrie A. THOMPSON, Lesley F. TINKER, Roberto TIRABOSCO, Anne TJONNELAND, Ruth C. TRAVIS, Dimitrios TRICHOPOULOS, Fang-Yu TSAI, Ying-Huang TSAI, Margaret TUCKER, Jenny TURNER, Claire M. VAJDIC, Roel C. H. VERMEULEN, Danylo J. VILLANO, Paolo VINEIS, Jarmo VIRTAMO, Kala VISVANATHAN, Jean WACTAWSKI-WENDE, Chaoyu WANG, Chih-Liang WANG, Jiu-Cun WANG, Junwen WANG, Fusheng WEI, Elisabete WEIDERPASS, George J. WEINER, Stephanie WEINSTEIN, Nicolas WENTZENSEN, Emily WHITE, Thomas E. WITZIG, Brian M. WOLPIN, Maria Pik WONG, Chen WU, Guoping WU, Junjie WU, Tangchun WU, Wei WU, Xifeng WU, Yi-Long WU, Jay S. WUNDER, Yong-Bing XIANG, Jun XU, Ping XU, Pan-Chyr YANG, Tsung-Ying YANG, Yuanqing YE, Zhihua YIN, Jun YOKOTA, Ho-ll YOON, Chong-Jen YU, Herbert YU, Kai YU, Jian-Min YUAN, Andrew ZELENETZ, Anne ZELENIUCH-JACQUOTTE, Xu-Chao ZHANG, Yawei ZHANG, Xueying ZHAO, Zhenhong ZHAO, Hong ZHENG, Tongzhang ZHENG, Wei ZHENG, Baosen ZHOU, Meng ZHU, Mariagrazia ZUCCA, Simina M. BOCA, James R. CERHAN, Giovanni M. FERRI, Patricia HARTGE, Chao Agnes HSIUNG, Corrado MAGNANI, Lucia MILIGI, Lindsay M. MORTON, Karin E. SMEDBY, Lauren R. TERAS, Joseph VIJAI, Sophia S. WANG, Paul BRENNAN, Neil E. CAPORASO, David J. HUNTER, Peter KRAFT, Nathaniel ROTHMAN, Debra T. SILVERMAN, Susan L. SLAGER, Stephen J. CHANOCK and Nilanjan CHATTERJEE. Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. CARY: OXFORD UNIV PRESS INC, 2015, vol. 107, No 12, p. 1-11. ISSN 0027-8874. Available from: https://dx.doi.org/10.1093/jnci/djv279. |
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@article{1340135, author = {Sampson, Joshua N. and Wheeler, William A. and Yeager, Meredith and Panagiotou, Orestis and Wang, Zhaoming and Berndt, Sonja I. and Lan, Qing and Abnet, Christian C. and Amundadottir, Laufey T. and Figueroa, Jonine D. and Landi, Maria Teresa and Mirabello, Lisa and Savage, Sharon A. and Taylor, Philip R. and DeVivo, Immaculata and McGlynn, Katherine A. and Purdue, Mark P. and Rajaraman, Preetha and Adami, HansandOlov and Ahlbom, Anders and Albanes, Demetrius and Amary, Maria Fernanda and An, SheandJuan and Andersson, Ulrika and Andriole, Gerald Jr. and Andrulis, Irene L. and Angelucci, Emanuele and Ansell, Stephen M. and Arici, Cecilia and Armstrong, Bruce K. and Arslan, Alan A. and Austin, Melissa A. and Baris, Dalsu and Barkauskas, Donald A. and Bassig, Bryan A. and Becker, Nikolaus and Benavente, Yolanda and Benhamou, Simone and Berg, Christine and Van Den Berg, David and Bernstein, Leslie and Bertrand, Kimberly A. and Birmann, Brenda M. and Black, Amanda and Boeing, Heiner and Boffetta, Paolo and BoutronandRuault, MarieandChristine and Bracci, Paige M. and Brinton, Louise and BrooksandWilson, Angela R. and BuenoandDeandMesquita, H. Bas and Burdett, Laurie and Buring, Julie and Butler, Mary Ann and Cai, Qiuyin and CancelandTassin, Geraldine and Canzian, Federico and Carrato, Alfredo and Carreon, Tania and Carta, Angela and Chan, John K.C. and Chang, Ellen T. and Chang, GeeandChen and Chang, IandShou and Chang, Jiang and ChangandClaude, Jenny and Chen, ChienandJen and Chen, ChinandYi and Chen, Chu and Chen, ChungandHsing and Chen, Constance and Chen, Hongyan and Chen, Kexin and Chen, KuanandYu and Chen, KunandChieh and Chen, Ying and Chen, YingandHsiang and Chen, YiandSong and Chen, YuhandMin and Chien, LiandHsin and Chirlaque, MariaandDolores and Choi, Jin Eun and Choi, Yi Young and Chow, WongandHo and Chung, Charles C. and Clavel, Jacqueline and ClavelandChapelon, Franoise and Cocco, Pierluigi and Colt, Joanne S. and Comperat, Eva and Conde, Lucia and Connors, Joseph M. and Conti, David and Cortessis, Victoria K. and Cotterchio, Michelle and Cozen, Wendy and Crouch, Simon and CrousandBou, Marta and Cussenot, Olivier and Davis, Faith G. and Ding, Ti and Diver, W. Ryan and Dorronsoro, Miren and Dossus, Laure and Duell, Eric J. and Ennas, Maria Grazia and Erickson, Ralph L. and Feychting, Maria and Flanagan, Adrienne M. and Foretová, Lenka and Fraumeni, Joseph F. Jr. and Freedman, Neal D. and Freeman, Laura E. Beane and Fuchs, Charles and GagoandDominguez, Manuela and Gallinger, Steven and Gao, YuandTang and Gapstur, Susan M. and GarciaandClosas, Montserrat and GarciaandClosas, Reina and Gascoyne, Randy D. and GastierandFoster, Julie and Gaudet, Mia M. and Gaziano, J. Michael and Giffen, Carol and Giles, Graham G. and Giovannucci, Edward and Glimelius, Bengt and Goggins, Michael and Gokgoz, Nalan and Goldstein, Alisa M. and Gorlick, Richard and Gross, Myron and Grubb, Robert III and Gu, Jian and Guan, Peng and Gunter, Marc and Guo, Huan and Habermann, Thomas M. and Haiman, Christopher A. and Halai, Dina and Hallmans, Goran and Hassan, Manal and Hattinger, Claudia and He, Qincheng and He, Xingzhou and Helzlsouer, Kathy and Henderson, Brian and Henriksson, Roger and Hjalgrim, Henrik and HoffmanandBolton, Judith and Hohensee, Chancellor and Holford, Theodore R. and Holly, Elizabeth A. and Hong, YunandChul and Hoover, Robert N. and HornandRoss, Pamela L. and Hosain, G.M. Monawar and Hosgood, H. Dean and Hsiao, ChinandFu and Hu, Nan and Hu, Wei and Hu, Zhibin and Huang, MingandShyan and Huerta, JoseandMaria and Hung, JenandYu and Hutchinson, Amy and Inskip, Peter D. and Jackson, Rebecca D. and Jacobs, Eric J. and Jenab, Mazda and Jeon, HyoandSung and Ji, BuandTian and Jin, Guangfu and Jin, Li and Johansen, Christoffer and Johnson, Alison and Jung, Yoo Jin and Kaaks, Rudolph and Kamineni, Aruna and Kane, Eleanor and Kang, Cang Hyan and Karagas, Margaret R. and Kelly, Rachel S. et al.}, article_location = {CARY}, article_number = {12}, doi = {http://dx.doi.org/10.1093/jnci/djv279}, keywords = {MULTIPLE SUSCEPTIBILITY LOCI; LUNG-CANCER; FAMILIAL RISK; PANCREATIC-CANCER; SWEDEN; INDIVIDUALS; MUTATIONS; RELATIVES; LYMPHOMA; DATABASE}, language = {eng}, issn = {0027-8874}, journal = {JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE}, title = {Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types}, volume = {107}, year = {2015} }
TY - JOUR ID - 1340135 AU - Sampson, Joshua N. - Wheeler, William A. - Yeager, Meredith - Panagiotou, Orestis - Wang, Zhaoming - Berndt, Sonja I. - Lan, Qing - Abnet, Christian C. - Amundadottir, Laufey T. - Figueroa, Jonine D. - Landi, Maria Teresa - Mirabello, Lisa - Savage, Sharon A. - Taylor, Philip R. - DeVivo, Immaculata - McGlynn, Katherine A. - Purdue, Mark P. - Rajaraman, Preetha - Adami, Hans-Olov - Ahlbom, Anders - Albanes, Demetrius - Amary, Maria Fernanda - An, She-Juan - Andersson, Ulrika - Andriole, Gerald Jr. - Andrulis, Irene L. - Angelucci, Emanuele - Ansell, Stephen M. - Arici, Cecilia - Armstrong, Bruce K. - Arslan, Alan A. - Austin, Melissa A. - Baris, Dalsu - Barkauskas, Donald A. - Bassig, Bryan A. - Becker, Nikolaus - Benavente, Yolanda - Benhamou, Simone - Berg, Christine - Van Den Berg, David - Bernstein, Leslie - Bertrand, Kimberly A. - Birmann, Brenda M. - Black, Amanda - Boeing, Heiner - Boffetta, Paolo - Boutron-Ruault, Marie-Christine - Bracci, Paige M. - Brinton, Louise - Brooks-Wilson, Angela R. - Bueno-De-Mesquita, H. Bas - Burdett, Laurie - Buring, Julie - Butler, Mary Ann - Cai, Qiuyin - Cancel-Tassin, Geraldine - Canzian, Federico - Carrato, Alfredo - Carreon, Tania - Carta, Angela - Chan, John K.C. - Chang, Ellen T. - Chang, Gee-Chen - Chang, I-Shou - Chang, Jiang - Chang-Claude, Jenny - Chen, Chien-Jen - Chen, Chin-Yi - Chen, Chu - Chen, Chung-Hsing - Chen, Constance - Chen, Hongyan - Chen, Kexin - Chen, Kuan-Yu - Chen, Kun-Chieh - Chen, Ying - Chen, Ying-Hsiang - Chen, Yi-Song - Chen, Yuh-Min - Chien, Li-Hsin - Chirlaque, Maria-Dolores - Choi, Jin Eun - Choi, Yi Young - Chow, Wong-Ho - Chung, Charles C. - Clavel, Jacqueline - Clavel-Chapelon, Franoise - Cocco, Pierluigi - Colt, Joanne S. - Comperat, Eva - Conde, Lucia - Connors, Joseph M. - Conti, David - Cortessis, Victoria K. - Cotterchio, Michelle - Cozen, Wendy - Crouch, Simon - Crous-Bou, Marta - Cussenot, Olivier - Davis, Faith G. - Ding, Ti - Diver, W. Ryan - Dorronsoro, Miren - Dossus, Laure - Duell, Eric J. - Ennas, Maria Grazia - Erickson, Ralph L. - Feychting, Maria - Flanagan, Adrienne M. - Foretová, Lenka - Fraumeni, Joseph F. Jr. - Freedman, Neal D. - Freeman, Laura E. Beane - Fuchs, Charles - Gago-Dominguez, Manuela - Gallinger, Steven - Gao, Yu-Tang - Gapstur, Susan M. - Garcia-Closas, Montserrat - Garcia-Closas, Reina - Gascoyne, Randy D. - Gastier-Foster, Julie - Gaudet, Mia M. - Gaziano, J. Michael - Giffen, Carol - Giles, Graham G. - Giovannucci, Edward - Glimelius, Bengt - Goggins, Michael - Gokgoz, Nalan - Goldstein, Alisa M. - Gorlick, Richard - Gross, Myron - Grubb, Robert III - Gu, Jian - Guan, Peng - Gunter, Marc - Guo, Huan - Habermann, Thomas M. - Haiman, Christopher A. - Halai, Dina - Hallmans, Goran - Hassan, Manal - Hattinger, Claudia - He, Qincheng - He, Xingzhou - Helzlsouer, Kathy - Henderson, Brian - Henriksson, Roger - Hjalgrim, Henrik - Hoffman-Bolton, Judith - Hohensee, Chancellor - Holford, Theodore R. - Holly, Elizabeth A. - Hong, Yun-Chul - Hoover, Robert N. - Horn-Ross, Pamela L. - Hosain, G.M. Monawar - Hosgood, H. Dean - Hsiao, Chin-Fu - Hu, Nan - Hu, Wei - Hu, Zhibin - Huang, Ming-Shyan - Huerta, Jose-Maria - Hung, Jen-Yu - Hutchinson, Amy - Inskip, Peter D. - Jackson, Rebecca D. - Jacobs, Eric J. - Jenab, Mazda - Jeon, Hyo-Sung - Ji, Bu-Tian - Jin, Guangfu - Jin, Li - Johansen, Christoffer - Johnson, Alison - Jung, Yoo Jin - Kaaks, Rudolph - Kamineni, Aruna - Kane, Eleanor - Kang, Cang Hyan - Karagas, Margaret R. - Kelly, Rachel S. et al. PY - 2015 TI - Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types JF - JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE VL - 107 IS - 12 SP - 1-11 EP - 1-11 PB - OXFORD UNIV PRESS INC SN - 00278874 KW - MULTIPLE SUSCEPTIBILITY LOCI KW - LUNG-CANCER KW - FAMILIAL RISK KW - PANCREATIC-CANCER KW - SWEDEN KW - INDIVIDUALS KW - MUTATIONS KW - RELATIVES KW - LYMPHOMA KW - DATABASE N2 - Background: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites. Methods: Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide association studies (GWAS) for 49 492 cancer case patients and 34 131 control patients. We apply novel mixed model methodology (GCTA) to this GWAS data to estimate the heritability of individual cancers, as well as the proportion of heritability attributable to cigarette smoking in smoking-related cancers, and the genetic correlation between pairs of cancers. Results: GWAS heritability was statistically significant at nearly all sites, with the estimates of array-based heritability, h(l)(2), on the liability threshold (LT) scale ranging from 0.05 to 0.38. Estimating the combined heritability of multiple smoking characteristics, we calculate that at least 24% (95% confidence interval [CI] = 14% to 37%) and 7% (95% CI = 4% to 11%) of the heritability for lung and bladder cancer, respectively, can be attributed to genetic determinants of smoking. Most pairs of cancers studied did not show evidence of strong genetic correlation. We found only four pairs of cancers with marginally statistically significant correlations, specifically kidney and testes (rho = 0.73, SE = 0.28), diffuse large B-cell lymphoma (DLBCL) and pediatric osteosarcoma (rho = 0.53, SE = 0.21), DLBCL and chronic lymphocytic leukemia (CLL) (rho = 0.51, SE = 0.18), and bladder and lung (rho = 0.35, SE = 0.14). Correlation analysis also indicates that the genetic architecture of lung cancer differs between a smoking population of European ancestry and a nonsmoking Asian population, allowing for the possibility that the genetic etiology for the same disease can vary by population and environmental exposures. Conclusion: Our results provide important insights into the genetic architecture of cancers and suggest new avenues for investigation. ER -
SAMPSON, Joshua N., William A. WHEELER, Meredith YEAGER, Orestis PANAGIOTOU, Zhaoming WANG, Sonja I. BERNDT, Qing LAN, Christian C. ABNET, Laufey T. AMUNDADOTTIR, Jonine D. FIGUEROA, Maria Teresa LANDI, Lisa MIRABELLO, Sharon A. SAVAGE, Philip R. TAYLOR, Immaculata DEVIVO, Katherine A. MCGLYNN, Mark P. PURDUE, Preetha RAJARAMAN, Hans-Olov ADAMI, Anders AHLBOM, Demetrius ALBANES, Maria Fernanda AMARY, She-Juan AN, Ulrika ANDERSSON, Gerald Jr. ANDRIOLE, Irene L. ANDRULIS, Emanuele ANGELUCCI, Stephen M. ANSELL, Cecilia ARICI, Bruce K. ARMSTRONG, Alan A. ARSLAN, Melissa A. AUSTIN, Dalsu BARIS, Donald A. BARKAUSKAS, Bryan A. BASSIG, Nikolaus BECKER, Yolanda BENAVENTE, Simone BENHAMOU, Christine BERG, David VAN DEN BERG, Leslie BERNSTEIN, Kimberly A. BERTRAND, Brenda M. BIRMANN, Amanda BLACK, Heiner BOEING, Paolo BOFFETTA, Marie-Christine BOUTRON-RUAULT, Paige M. BRACCI, Louise BRINTON, Angela R. BROOKS-WILSON, H. Bas BUENO-DE-MESQUITA, Laurie BURDETT, Julie BURING, Mary Ann BUTLER, Qiuyin CAI, Geraldine CANCEL-TASSIN, Federico CANZIAN, Alfredo CARRATO, Tania CARREON, Angela CARTA, John K.C. CHAN, Ellen T. CHANG, Gee-Chen CHANG, I-Shou CHANG, Jiang CHANG, Jenny CHANG-CLAUDE, Chien-Jen CHEN, Chin-Yi CHEN, Chu CHEN, Chung-Hsing CHEN, Constance CHEN, Hongyan CHEN, Kexin CHEN, Kuan-Yu CHEN, Kun-Chieh CHEN, Ying CHEN, Ying-Hsiang CHEN, Yi-Song CHEN, Yuh-Min CHEN, Li-Hsin CHIEN, Maria-Dolores CHIRLAQUE, Jin Eun CHOI, Yi Young CHOI, Wong-Ho CHOW, Charles C. CHUNG, Jacqueline CLAVEL, Franoise CLAVEL-CHAPELON, Pierluigi COCCO, Joanne S. COLT, Eva COMPERAT, Lucia CONDE, Joseph M. CONNORS, David CONTI, Victoria K. CORTESSIS, Michelle COTTERCHIO, Wendy COZEN, Simon CROUCH, Marta CROUS-BOU, Olivier CUSSENOT, Faith G. DAVIS, Ti DING, W. Ryan DIVER, Miren DORRONSORO, Laure DOSSUS, Eric J. DUELL, Maria Grazia ENNAS, Ralph L. ERICKSON, Maria FEYCHTING, Adrienne M. FLANAGAN, Lenka FORETOVÁ, Joseph F. Jr. FRAUMENI, Neal D. FREEDMAN, Laura E. Beane FREEMAN, Charles FUCHS, Manuela GAGO-DOMINGUEZ, Steven GALLINGER, Yu-Tang GAO, Susan M. GAPSTUR, Montserrat GARCIA-CLOSAS, Reina GARCIA-CLOSAS, Randy D. GASCOYNE, Julie GASTIER-FOSTER, Mia M. GAUDET, J. Michael GAZIANO, Carol GIFFEN, Graham G. GILES, Edward GIOVANNUCCI, Bengt GLIMELIUS, Michael GOGGINS, Nalan GOKGOZ, Alisa M. GOLDSTEIN, Richard GORLICK, Myron GROSS, Robert III GRUBB, Jian GU, Peng GUAN, Marc GUNTER, Huan GUO, Thomas M. HABERMANN, Christopher A. HAIMAN, Dina HALAI, Goran HALLMANS, Manal HASSAN, Claudia HATTINGER, Qincheng HE, Xingzhou HE, Kathy HELZLSOUER, Brian HENDERSON, Roger HENRIKSSON, Henrik HJALGRIM, Judith HOFFMAN-BOLTON, Chancellor HOHENSEE, Theodore R. HOLFORD, Elizabeth A. HOLLY, Yun-Chul HONG, Robert N. HOOVER, Pamela L. HORN-ROSS, G.M. Monawar HOSAIN, H. Dean HOSGOOD, Chin-Fu HSIAO, Nan HU, Wei HU, Zhibin HU, Ming-Shyan HUANG, Jose-Maria HUERTA, Jen-Yu HUNG, Amy HUTCHINSON, Peter D. INSKIP, Rebecca D. JACKSON, Eric J. JACOBS, Mazda JENAB, Hyo-Sung JEON, Bu-Tian JI, Guangfu JIN, Li JIN, Christoffer JOHANSEN, Alison JOHNSON, Yoo Jin JUNG, Rudolph KAAKS, Aruna KAMINENI, Eleanor KANE, Cang Hyan KANG, Margaret R. KARAGAS, Rachel S. KELLY, Kay-Tee KHAW, Christopher KIM, Hee Nam KIM, Jin Hee KIM, Jun Suk KIM, Yeul Hong KIM, Young Tae KIM, Young Chul KIM, Cari M. KITAHARA, Alison P. KLEIN, Robert J. KLEIN, Manolis KOGEVINAS, Takashi KOHNO, Laurence N. KOLONEL, Charles KOOPERBERG, Anne KRICKER, Vittorio KROGH, Hideo KUNITOH, Robert C. KURTZ, Sun-Seog KWEON, Andrea LACROIX, Charles LAWRENCE, Fernando LECANDA, Victor Ho Fun LEE, Donghui LI, Haixin LI, Jihua LI, Yao-Jen LI, Yyqing LI, Linda M. LIAO, Mark LIEBOW, Tracy LIGHTFOOT, Wei-Yen LIM, Chien-Chung LIN, Dongxin LIN, Sasa LINDSTROM, Martha S. LINET, Brian K. 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