Detailed Information on Publication Record

GERŠLOVÁ, Alena, Andrea POKORNÁ, Alena ŠTUKAVCOVA and Lenka VEVERKOVÁ. Rare cause of non-healing foot wound - acral lentiginous melanoma. Neuroendocrinology Letters. Stockholm: Maghira and Maas Publications, 2016, vol. 37, No 1, p. 12-17. ISSN 0172-780X.

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Basic information
Original name	Rare cause of non-healing foot wound - acral lentiginous melanoma
Authors	GERŠLOVÁ, Alena (203 Czech Republic, guarantor), Andrea POKORNÁ (203 Czech Republic, belonging to the institution), Alena ŠTUKAVCOVA (203 Czech Republic) and Lenka VEVERKOVÁ (203 Czech Republic, belonging to the institution).
Edition	Neuroendocrinology Letters, Stockholm, Maghira and Maas Publications, 2016, 0172-780X.

Other information
Original language	English
Type of outcome	Article in a journal
Field of Study	30200 3.2 Clinical medicine
Country of publisher	Sweden
Confidentiality degree	is not subject to a state or trade secret
WWW	URL
Impact factor	Impact factor: 0.918
RIV identification code	RIV/00216224:14110/16:00089629
Organization unit	Faculty of Medicine
UT WoS	000373446900003
Keywords in English	diagnostic techniques; examination; foot; malignant melanoma; ulcer; wound
Tags	EL OK
Tags	International impact, Reviewed
Changed by	Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 4/8/2016 15:33.

Abstract
The etiology of skin integrity disorders of the lower extremities can be very diverse. In addition to common diagnoses such as venous ulcers with ischemic etiology, decubitus ulcers and diabetic foot syndrome, ulceration of a malignant etiology must also be considered. Malignant melanoma is one of the most dangerous forms of skin cancer and, although rare, may cause foot lesions. The most frequently encountered type of melanoma on acral parts of the limbs is the rare acral lentiginous variant, which only occurs in 2-10% of all melanoma types. Clinical manifestation ranges from cutaneous surface erosion to ulceration with surrounding hyperkeratosis, which can cause considerable differential diagnostic difficulties in the management of patients with non-healing foot wounds. This paper aims to present a clear case study of a Caucasian female with chronic leg ulceration that resulted in a final diagnosis of malignant acral lentiginous melanoma. Supplemental theoretical information regarding the diagnosis and treatment of malignant melanoma has also been included in the report. Malignant acral lentiginous melanoma is a rare cause of non-healing wounds, but it must be considered in cases with long-term healing complications. Precise diagnostic deliberation is crucial in the management and treatment of all chronic and long-term non-healing lesions, and appropriately performed biopsies are essential to determine whether malignancy is the primary cause.

Abstract

The etiology of skin integrity disorders of the lower extremities can be very diverse. In addition to common diagnoses such as venous ulcers with ischemic etiology, decubitus ulcers and diabetic foot syndrome, ulceration of a malignant etiology must also be considered. Malignant melanoma is one of the most dangerous forms of skin cancer and, although rare, may cause foot lesions. The most frequently encountered type of melanoma on acral parts of the limbs is the rare acral lentiginous variant, which only occurs in 2-10% of all melanoma types. Clinical manifestation ranges from cutaneous surface erosion to ulceration with surrounding hyperkeratosis, which can cause considerable differential diagnostic difficulties in the management of patients with non-healing foot wounds. This paper aims to present a clear case study of a Caucasian female with chronic leg ulceration that resulted in a final diagnosis of malignant acral lentiginous melanoma. Supplemental theoretical information regarding the diagnosis and treatment of malignant melanoma has also been included in the report. Malignant acral lentiginous melanoma is a rare cause of non-healing wounds, but it must be considered in cases with long-term healing complications. Precise diagnostic deliberation is crucial in the management and treatment of all chronic and long-term non-healing lesions, and appropriately performed biopsies are essential to determine whether malignancy is the primary cause.