| SVOBODA, Petr, I KANTOROVA, L KOZUMPLIK, P SCHEER, M RADVAN, Jarmila RADVANOVÁ, Vladimír KRASS and F HORALEK. Our Experience with Transoral Incisionless Plication of Gastroesophageal Reflux Disease: NOTES Procedure. Hepato-gastroenterology. ATHENS: H G E UPDATE MEDICAL PUBLISHING S A, 2011, vol. 58, No 109, p. 1208-1213. ISSN 0172-6390. |
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@article{1343595,
author = {Svoboda, Petr and Kantorova, I and Kozumplik, L and Scheer, P and Radvan, M and Radvanová, Jarmila and Krass, Vladimír and Horalek, F},
article_location = {ATHENS},
article_number = {109},
keywords = {NOTES; Gastroesophageal; Reflux; Disease; Plication},
language = {eng},
issn = {0172-6390},
journal = {Hepato-gastroenterology},
title = {Our Experience with Transoral Incisionless Plication of Gastroesophageal Reflux Disease: NOTES Procedure},
volume = {58},
year = {2011}
}
TY - JOUR
ID - 1343595
AU - Svoboda, Petr - Kantorova, I - Kozumplik, L - Scheer, P - Radvan, M - Radvanová, Jarmila - Krass, Vladimír - Horalek, F
PY - 2011
TI - Our Experience with Transoral Incisionless Plication of Gastroesophageal Reflux Disease: NOTES Procedure
JF - Hepato-gastroenterology
VL - 58
IS - 109
SP - 1208-1213
EP - 1208-1213
PB - H G E UPDATE MEDICAL PUBLISHING S A
SN - 01726390
KW - NOTES
KW - Gastroesophageal
KW - Reflux
KW - Disease
KW - Plication
N2 - Background/Aims. Natural Orifice Trans luminal Surgery (NOTES) has been introduced in endoscopic surgery as a new system offering the advantage of a less invasive procedure. Gastroesophageal reflux disease (GERD) appears to be the most promising application of NOTES treatment. The aims of our study were to evaluate the safety and efficacy of this procedure and length of hospital stay. Methodology: Patients indicated for surgery of GERD were randomly assigned (ratio 2:1) to transoral incisionless fundoplication (TIF group, n=34) and control group, where gold standard Nissen laparoscopic fundoplication was performed (NLF group, n=18). For TIF the Plicator (R) method was initially used for 18 patients, but the company terminated production in 2008 without a follower. During the last 2 years the EsophyX (R) method was used for 16 patients. Results: After the evaluation of 34 TIF patients and 18 NLF patients we observed similar efficacy of TIF procedures compared with NLF after 3 and 12 months. The hospital stay was significantly shorter (p<0.0001) in TIF group (average, 2.9 +/- 0.8 days) than in NLF group (6.4 +/- 0.7). The TIF procedure was safe; we observed 1 serious adverse event in the TIF group and 3 in the NLF group. Conclusions: It can be summarized that both NOTES TIF procedures are, after the initial learning curve, safe and effective methods for treatment of GERD, allowing substantial shortening of hospital stay. The effect of both procedures was sustained over 12 months. Longer follow-up is necessary to verify efficacy for more years.
ER -
SVOBODA, Petr, I KANTOROVA, L KOZUMPLIK, P SCHEER, M RADVAN, Jarmila RADVANOVÁ, Vladimír KRASS and F HORALEK. Our Experience with Transoral Incisionless Plication of Gastroesophageal Reflux Disease: NOTES Procedure. \textit{Hepato-gastroenterology}. ATHENS: H G E UPDATE MEDICAL PUBLISHING S A, 2011, vol.~58, No~109, p.~1208-1213. ISSN~0172-6390.
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