High-yield expression of OspC protein from B. burgdorferi, isolation of monoclonal antibodies and epitope mapping

NOREK, Adam, Silvie LIŠKOVÁ and Lubomír JANDA. High-yield expression of OspC protein from B. burgdorferi, isolation of monoclonal antibodies and epitope mapping. In Ľubica Urbániková, Barbora Vidová, Zuzana Šrámková. 4th Conference on Protein : Naše proteíny 2016 - Štruktúra a funkcia. Bratislava (Slovakia): Institute of Molecular Biology, SAS, Bratislava, 2016, p. 24-25. ISBN 978-80-971617-1-2.

Basic information

• Original name: High-yield expression of OspC protein from B. burgdorferi, isolation of monoclonal antibodies and epitope mapping
• Authors: NOREK, Adam (203 Czech Republic, guarantor, belonging to the institution), Silvie LIŠKOVÁ (203 Czech Republic, belonging to the institution) and Lubomír JANDA (203 Czech Republic, belonging to the institution).
• Edition: Bratislava (Slovakia), 4th Conference on Protein : Naše proteíny 2016 - Štruktúra a funkcia, p. 24-25, 2 pp. 2016.
• Publisher: Institute of Molecular Biology, SAS, Bratislava

Other information

• Original language: English
• Type of outcome: Proceedings paper
• Field of Study: Genetics and molecular biology
• Country of publisher: Slovakia
• Confidentiality degree: is not subject to a state or trade secret
• Publication form: printed version "print"
• RIV identification code: RIV/00216224:14740/16:00089916
• Organization unit: Central European Institute of Technology
• ISBN: 978-80-971617-1-2
• Keywords in English: OspC; expression; monoclonal antibodies; epitope

Abstract

The aim of our study was to prepare recombinant forms of OspC protein (Borrelia burgdorferi s.l.) relevant for the Czech Republic and prepare a set of monoclonal antibodies with a high affinity to OspC protein and determine recognised epitopes.

Links

• LQ1601, research and development project: Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR