SVOBODA, David, Vladimír ULMAN, Peter KOVÁČ, Barbara ŠALINGOVÁ, Lenka TESAŘOVÁ, Irena KRONTORÁD KOUTNÁ and Petr MATULA. Vascular Network Formation in Silico Using the Extended Cellular Potts Model. In 2016 IEEE International Conference on Image Processing. Piscataway, NJ, USA: IEEE Signal Processing Society, 2016, p. 3180-3183. ISBN 978-1-4673-9961-6. Available from: https://dx.doi.org/10.1109/ICIP.2016.7532946.
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Basic information
Original name Vascular Network Formation in Silico Using the Extended Cellular Potts Model
Authors SVOBODA, David (203 Czech Republic, guarantor, belonging to the institution), Vladimír ULMAN (203 Czech Republic, belonging to the institution), Peter KOVÁČ (703 Slovakia, belonging to the institution), Barbara ŠALINGOVÁ (703 Slovakia, belonging to the institution), Lenka TESAŘOVÁ (203 Czech Republic, belonging to the institution), Irena KRONTORÁD KOUTNÁ (203 Czech Republic, belonging to the institution) and Petr MATULA (203 Czech Republic, belonging to the institution).
Edition Piscataway, NJ, USA, 2016 IEEE International Conference on Image Processing, p. 3180-3183, 4 pp. 2016.
Publisher IEEE Signal Processing Society
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form storage medium (CD, DVD, flash disk)
WWW URL
RIV identification code RIV/00216224:14330/16:00087993
Organization unit Faculty of Informatics
ISBN 978-1-4673-9961-6
ISSN 1522-4880
Doi http://dx.doi.org/10.1109/ICIP.2016.7532946
UT WoS 000390782003040
Keywords in English Synthetic image formation; Vascular network; Cellular Potts model; Angiogenesis
Tags CBIA, cbia-web, firank_A
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Petr Matula, Ph.D., učo 3019. Changed: 12/2/2018 14:54.
Abstract
Cardiovascular diseases belong to the most widespread illnesses in the developed countries. Therefore, the regenerative medicine and tissue modeling applications are highly interested in studying the ability of endothelial cells, derived from human stem cells, to form vascular networks. Several characteristics can be measured on images of these networks and hence describe the quality of the endothelial cells. With advances in the image processing, automatic analysis of these complex images becomes increasingly common. In this study, we introduce a new graph structure and additional constraints to the cellular Potts model, a framework commonly utilized in computational biology. Our extension allows to generate visually plausible synthetic image sequences of evolving fluorescently labeled vascular networks with ground truth data. Such generated datasets can be subsequently used for testing and validating methods employed for the analysis and measurement of the images of real vascular networks.
Links
GA14-22461S, research and development projectName: Vývoj a studium metod pro kvantifikaci živých buněk (Acronym: Live Cell Quantification)
Investor: Czech Science Foundation
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