| GANOVSKÁ, Eva, Mattia ARRIGO, Kateřina HELÁNOVÁ, Simona LITTNEROVÁ, Malha SADOUNE, Petr KUBENA, Marie PAVLUŠOVÁ, Jiří JARKOVSKÝ, Jana GOTTWALDOVÁ, Petr KALA, Milan DASTYCH, Shiro ISHIHARA, Lucas N.L. VAN AELST, Alain COHEN-SOLAL, Etienne GAYAT, Jindřich ŠPINAR, Jiří PAŘENICA and Alexandre MEBAZAA. Natriuretic peptides in addition to Zwolle score to enhance safe and early discharge after acute myocardial infarction: A prospective observational cohort study. International Journal of Cardiology. Clare (Ireland): Elsevier Ireland Ltd., 2016, vol. 215, JUL 15 2016, p. 527-531. ISSN 0167-5273. Available from: https://dx.doi.org/10.1016/j.ijcard.2016.04.148. |
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@article{1350797,
author = {Ganovská, Eva and Arrigo, Mattia and Helánová, Kateřina and Littnerová, Simona and Sadoune, Malha and Kubena, Petr and Pavlušová, Marie and Jarkovský, Jiří and Gottwaldová, Jana and Kala, Petr and Dastych, Milan and Ishihara, Shiro and Van Aelst, Lucas N.L. and CohenandSolal, Alain and Gayat, Etienne and Špinar, Jindřich and Pařenica, Jiří and Mebazaa, Alexandre},
article_location = {Clare (Ireland)},
article_number = {JUL 15 2016},
doi = {http://dx.doi.org/10.1016/j.ijcard.2016.04.148},
keywords = {Myocardial infarction; STEMI; Discharge; Zwolle; BNP},
language = {eng},
issn = {0167-5273},
journal = {International Journal of Cardiology},
title = {Natriuretic peptides in addition to Zwolle score to enhance safe and early discharge after acute myocardial infarction: A prospective observational cohort study},
volume = {215},
year = {2016}
}
TY - JOUR
ID - 1350797
AU - Ganovská, Eva - Arrigo, Mattia - Helánová, Kateřina - Littnerová, Simona - Sadoune, Malha - Kubena, Petr - Pavlušová, Marie - Jarkovský, Jiří - Gottwaldová, Jana - Kala, Petr - Dastych, Milan - Ishihara, Shiro - Van Aelst, Lucas N.L. - Cohen-Solal, Alain - Gayat, Etienne - Špinar, Jindřich - Pařenica, Jiří - Mebazaa, Alexandre
PY - 2016
TI - Natriuretic peptides in addition to Zwolle score to enhance safe and early discharge after acute myocardial infarction: A prospective observational cohort study
JF - International Journal of Cardiology
VL - 215
IS - JUL 15 2016
SP - 527-531
EP - 527-531
PB - Elsevier Ireland Ltd.
SN - 01675273
KW - Myocardial infarction
KW - STEMI
KW - Discharge
KW - Zwolle
KW - BNP
N2 - Background: The Zwolle score is recommended to identify low-risk patients eligible for early hospital discharge after ST-elevation myocardial infarction (STEMI), but since only one third of STEMI has low Zwolle score, hospital discharge is frequently delayed. B-type natriuretic peptide (BNP) also provides prognostic information after STEMI. The aim of the study was to test the hypothesis that patients with high Zwolle score associated with low BNP share similar outcomes than those with low Zwolle score. Methods and results: The study population consisted of 1032 consecutive STEMI patients in whom BNP was measured 24 h after chest pain onset. The area under the curve of Zwolle score and plasma BNP for 30-day mortality were 0.82 and 0.87, p = 0.39. A BNP threshold of 200 pg/ml had sensitivity of 100% and specificity of 34% for predicting 30-day mortality. Patients with high Zwolle score and BNP = 200 pg/ml (n = 183) had similar mortality and hospital stay to those with low Zwolle score (0% vs. 0.5% and 5 vs. 5 days, both p= 1.0). By contrast, patients with high Zwolle score and BNP > 200 pg/ml had the highest mortality (6.7%) and the longest hospital stay (6 days), both p < 0.01. Conclusion: STEMI patients with high Zwolle score but low BNP share similar outcomes with those with low Zwolle score and should be eligible for early discharge. Hence, using the rule of "low-Zwolle or low-BNP" might increase the number of STEMI patients that might be eligible for early discharge.
ER -
GANOVSKÁ, Eva, Mattia ARRIGO, Kateřina HELÁNOVÁ, Simona LITTNEROVÁ, Malha SADOUNE, Petr KUBENA, Marie PAVLUŠOVÁ, Jiří JARKOVSKÝ, Jana GOTTWALDOVÁ, Petr KALA, Milan DASTYCH, Shiro ISHIHARA, Lucas N.L. VAN AELST, Alain COHEN-SOLAL, Etienne GAYAT, Jindřich ŠPINAR, Jiří PAŘENICA and Alexandre MEBAZAA. Natriuretic peptides in addition to Zwolle score to enhance safe and early discharge after acute myocardial infarction: A prospective observational cohort study. \textit{International Journal of Cardiology}. Clare (Ireland): Elsevier Ireland Ltd., 2016, vol.~215, JUL 15 2016, p.~527-531. ISSN~0167-5273. Available from: https://dx.doi.org/10.1016/j.ijcard.2016.04.148.
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