Asymptomatic Elevation of Amylase and Lipase After Olanzapine Treatment

USTOHAL, Libor, Michaela MAYEROVÁ, Barbora VALKOVÁ, Hana SEDLÁKOVÁ and Tomáš KAŠPÁREK. Asymptomatic Elevation of Amylase and Lipase After Olanzapine Treatment. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS, 2016, vol. 36, No 2, p. 181-183. ISSN 0271-0749. Available from: https://dx.doi.org/10.1097/JCP.0000000000000460.

Basic information

• Original name: Asymptomatic Elevation of Amylase and Lipase After Olanzapine Treatment
• Authors: USTOHAL, Libor (203 Czech Republic, guarantor, belonging to the institution), Michaela MAYEROVÁ (203 Czech Republic, belonging to the institution), Barbora VALKOVÁ (203 Czech Republic, belonging to the institution), Hana SEDLÁKOVÁ (203 Czech Republic) and Tomáš KAŠPÁREK (203 Czech Republic, belonging to the institution).
• Edition: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, PHILADELPHIA, LIPPINCOTT WILLIAMS & WILKINS, 2016, 0271-0749.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30104 Pharmacology and pharmacy
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 2.891
• RIV identification code: RIV/00216224:14740/16:00090599
• Organization unit: Central European Institute of Technology
• Doi: http://dx.doi.org/10.1097/JCP.0000000000000460
• UT WoS: 000372100800018
• Keywords in English: ACUTE-PANCREATITIS
• Tags: EL OK, podil, rivok

Abstract

Olanzapine, an atypical antipsychotic,has been considered one of the most efficient antipsychotic drugs, and it is the most frequently prescribed. It is categorized as a multiacting receptor targeted antipsychotic. The most significant adverse effects of olanzapine are metabolic: acute pancreatitis is one of the most serious adverse effects; fortunately, it does not occur very often. Koller et al1 found 51 cases,and at least 13 cases have been described more precisely. We present a case study of a young female patient with a very fast and high increase of amylase and lipase, who remained asymptomatic, immediately after olanzapine treatment.

Links

• LQ1601, research and development project: Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR