CORNELISSEN, Germaine, Jarmila SIEGELOVÁ, Alena HAVELKOVÁ, Leona DUNKLEROVÁ and Jiří DUŠEK. Changes with Age in the Time Structure of Blood Pressure. World Heart Journal. New York: Nova Science Publishers Inc, 2016, vol. 8, No 2, p. 141-156. ISSN 1556-4002.
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Basic information
Original name Changes with Age in the Time Structure of Blood Pressure
Authors CORNELISSEN, Germaine (840 United States of America), Jarmila SIEGELOVÁ (203 Czech Republic, guarantor, belonging to the institution), Alena HAVELKOVÁ (203 Czech Republic, belonging to the institution), Leona DUNKLEROVÁ (203 Czech Republic, belonging to the institution) and Jiří DUŠEK (203 Czech Republic).
Edition World Heart Journal, New York, Nova Science Publishers Inc, 2016, 1556-4002.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/16:00090619
Organization unit Faculty of Medicine
Keywords in English Aging; Blood pressure; Circadian; Heart rate; Infradian; Ultradian; Variance transposition
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 24/8/2016 12:44.
Abstract
To map changes in the time structure of blood pressure as a function of age, we analyze 7-day/24-hour records obtained by ambulatory blood pressure monitoring. From January 2000 to June 2011, 297 records were obtained (78 from women and 219 from men). Subjects were 20 to 84 years of age. They resided in Brno, Czech Republic, and were mostly clinically healthy at the time of monitoring. All but 23 records covered a week. Data from the 274 complete records were analyzed by least squares spectrum in the frequency range from 1 cycle per week to 12 cycles per day. Population-mean cosinor spectra were obtained to assess the infradian-to-circadian (frequencies of 1 to 7 cycles per week) and circadian-to-ultradian (frequencies between 1 and 7 cycles per day) spectral domains. With increasing age, the circadian amplitude of blood pressure was reduced and the circadian acrophase of blood pressure was advanced. There was also a transposition of the variance from the circadian to both the infradian and ultradian domains. These results are in keeping with a previous investigation of a less homogeneous population. They provide further evidence for the need to refine reference standards by accounting for changes with age in circadian (and other) rhythm characteristics.
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