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@article{1352266, author = {Križanová, Oľga and Babula, Petr and Pacak, K.}, article_location = {Abingdon}, article_number = {4}, doi = {http://dx.doi.org/10.1080/10253890.2016.1203415}, keywords = {Adrenergic receptors; beta-blockers; catecholamines; dopamine; epinephrine; norepinephrine; stress; tumor}, language = {eng}, issn = {1025-3890}, journal = {Stress}, title = {Stress, catecholaminergic system and cancer}, volume = {19}, year = {2016} }
TY - JOUR ID - 1352266 AU - Križanová, Oľga - Babula, Petr - Pacak, K. PY - 2016 TI - Stress, catecholaminergic system and cancer JF - Stress VL - 19 IS - 4 SP - 419-428 EP - 419-428 PB - Taylor & Francis LTD SN - 10253890 KW - Adrenergic receptors KW - beta-blockers KW - catecholamines KW - dopamine KW - epinephrine KW - norepinephrine KW - stress KW - tumor N2 - Stress as a modern civilization factor significantly affects our lives. While acute stress might have a positive effect on the organism, chronic stress is usually detrimental and might lead to serious health complications. It is known that stress induced by the physical environment (temperature-induced cold stress) can significantly impair the efficacy of cytotoxic chemotherapies and the anti-tumor immune response. On the other hand, epidemiological evidence has shown that patients taking drugs known as beta-adrenergic antagonists ("beta-blockers"), which are commonly prescribed to treat arrhythmia, hypertension, and anxiety, have significantly lower rates of several cancers. In this review, we summarize the current knowledge about catecholamines as important stress hormones in tumorigenesis and discuss the use of beta-blockers as the potential therapeutic agents. ER -
KRIŽANOVÁ, Oľga, Petr BABULA a K. PACAK. Stress, catecholaminergic system and cancer. \textit{Stress}. Abingdon: Taylor \&{} Francis LTD, 2016, roč.~19, č.~4, s.~419-428. ISSN~1025-3890. Dostupné z: https://dx.doi.org/10.1080/10253890.2016.1203415.
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