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@article{1352266,
author = {Križanová, Oľga and Babula, Petr and Pacak, K.},
article_location = {Abingdon},
article_number = {4},
doi = {http://dx.doi.org/10.1080/10253890.2016.1203415},
keywords = {Adrenergic receptors; beta-blockers; catecholamines; dopamine; epinephrine; norepinephrine; stress; tumor},
language = {eng},
issn = {1025-3890},
journal = {Stress},
title = {Stress, catecholaminergic system and cancer},
volume = {19},
year = {2016}
}
TY - JOUR
ID - 1352266
AU - Križanová, Oľga - Babula, Petr - Pacak, K.
PY - 2016
TI - Stress, catecholaminergic system and cancer
JF - Stress
VL - 19
IS - 4
SP - 419-428
EP - 419-428
PB - Taylor & Francis LTD
SN - 10253890
KW - Adrenergic receptors
KW - beta-blockers
KW - catecholamines
KW - dopamine
KW - epinephrine
KW - norepinephrine
KW - stress
KW - tumor
N2 - Stress as a modern civilization factor significantly affects our lives. While acute stress might have a positive effect on the organism, chronic stress is usually detrimental and might lead to serious health complications. It is known that stress induced by the physical environment (temperature-induced cold stress) can significantly impair the efficacy of cytotoxic chemotherapies and the anti-tumor immune response. On the other hand, epidemiological evidence has shown that patients taking drugs known as beta-adrenergic antagonists ("beta-blockers"), which are commonly prescribed to treat arrhythmia, hypertension, and anxiety, have significantly lower rates of several cancers. In this review, we summarize the current knowledge about catecholamines as important stress hormones in tumorigenesis and discuss the use of beta-blockers as the potential therapeutic agents.
ER -
KRIŽANOVÁ, Oľga, Petr BABULA a K. PACAK. Stress, catecholaminergic system and cancer. \textit{Stress}. Abingdon: Taylor \&{} Francis LTD, 2016, roč.~19, č.~4, s.~419-428. ISSN~1025-3890. Dostupné z: https://dx.doi.org/10.1080/10253890.2016.1203415.
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