KREJČÍ, Jan, Dalibor MLEJNEK, Dana SOCHOROVÁ and Petr NĚMEC. Inflammatory Cardiomyopathy: A Current View on the Pathophysiology, Diagnosis, and Treatment. Biomed Research International. New York: Hindawi Publishing Corporation, 2016, vol. 2016, No 4087632, p. 1-11. ISSN 2314-6133. Available from: https://dx.doi.org/10.1155/2016/4087632.
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Basic information
Original name Inflammatory Cardiomyopathy: A Current View on the Pathophysiology, Diagnosis, and Treatment
Authors KREJČÍ, Jan (203 Czech Republic, belonging to the institution), Dalibor MLEJNEK (203 Czech Republic, belonging to the institution), Dana SOCHOROVÁ (203 Czech Republic, belonging to the institution) and Petr NĚMEC (203 Czech Republic, guarantor, belonging to the institution).
Edition Biomed Research International, New York, Hindawi Publishing Corporation, 2016, 2314-6133.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.476
RIV identification code RIV/00216224:14110/16:00090788
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1155/2016/4087632
UT WoS 000378704900001
Keywords in English GIANT-CELL MYOCARDITIS; CARDIOVASCULAR MAGNETIC-RESONANCE; VENTRICULAR ENDOMYOCARDIAL BIOPSY; ACUTE VIRAL MYOCARDITIS; ONSET DILATED CARDIOMYOPATHY; HEART-FAILURE ASSOCIATION
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 12/9/2016 13:01.
Abstract
Inflammatory cardiomyopathy is defined as inflammation of the heart muscle associated with impaired function of the myocardium. In our region, its etiology is most often viral. Viral infection is a possible trigger of immune and autoimmune mechanisms which contributed to the damage of myocardial function. Myocarditis is considered the most common cause of dilated cardiomyopathy. Typical manifestation of this disease is heart failure, chest pain, or arrhythmias. The most important noninvasive diagnostic method is magnetic resonance imaging, but the gold standard of diagnostics is invasive examination, endomyocardial biopsy. In a significant proportion of cases with impaired left ventricular systolic function, recovery occurs spontaneously in several weeks and therefore it is appropriate to postpone critical therapeutic decisions about 3-6 months after start of the treatment. Therapy is based on standard heart failure treatment; immunosuppressive or antimicrobial treatment may be considered in some cases depending on the results of endomyocardial biopsy. If severe dysfunction of the left ventricle persists, device therapy may be needed.
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