Detailed Information on Publication Record
2016
c-MET-mediated resistance to EGFR inhibitors in head and neck cancer: How to move from bench to bedside
SZTURZ, Petr, E. RAYMOND and S. FAIVREBasic information
Original name
c-MET-mediated resistance to EGFR inhibitors in head and neck cancer: How to move from bench to bedside
Authors
SZTURZ, Petr (203 Czech Republic, guarantor, belonging to the institution), E. RAYMOND (250 France) and S. FAIVRE (250 France)
Edition
Oral oncology, AMSTERDAM, ELSEVIER SCIENCE BV, 2016, 1368-8375
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30200 3.2 Clinical medicine
Country of publisher
Netherlands
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 4.794
RIV identification code
RIV/00216224:14110/16:00090826
Organization unit
Faculty of Medicine
UT WoS
000380544000005
Keywords in English
squamous-cell carcinoma; randomized phase-ii; tivantinib arq 197; lung-cancer; acquired-resistance; metastatic head; plus erlotinib; double-blind; patients pts; placebo
Tags
Tags
International impact, Reviewed
Změněno: 15/9/2016 15:09, Soňa Böhmová
Abstract
V originále
Mesenchymal–epithelial transition factor (c-MET), found on melanocytes, endothelial cells, and epithelial tissues, is a membrane spanning receptor tyrosine kinase for hepatocyte growth factor (HGF), produced by elements of mesenchymal origin. The receptor-ligand pair controls diverse biological activities including cell proliferation, motility, invasiveness, morphogenesis, apoptosis, and angiogenesis.