Injuries are a current and relevant factors that threaten the lives and health of children. The higher probability of their occurrence is associated with the study at professional and vocational schools. Therefore, it is imperative that teachers and pupils knew well the principles of safety and the basics of first aid. The survey was carried out on a pilot sample of 80 pupils from 2 secondary schools in the Brno region. To collect the data was used non-standardized anonymous 25 items questionnaire, supplemented by 8 items interviews with teachers in charge of first aid and accident prevention in schools. Data were electronically recorded and statistically evaluated. They were found numerous deficiencies in the teaching of first aid, which is either completely missing or incoherent. Safety and health protection when handling machines and tools are treated solidly, knowledge of first aid at pupils are significant reserves and will need to improve their training.