a 2016

Neuromodulation in Hypertension

NECHUTOVÁ, Hana, Miroslav SOUČEK, K. BRABENCOVA, R. STEPANOVA, Mojmír BLAHA et. al.

Basic information

Original name

Neuromodulation in Hypertension

Authors

NECHUTOVÁ, Hana (203 Czech Republic, guarantor, belonging to the institution), Miroslav SOUČEK (203 Czech Republic, belonging to the institution), K. BRABENCOVA (203 Czech Republic), R. STEPANOVA (203 Czech Republic), Mojmír BLAHA (203 Czech Republic, belonging to the institution) and Jiří VANÍČEK (203 Czech Republic, belonging to the institution)

Edition

26th European Meeting on Hypertension and Cardiovascular Protection, 2016

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.085

RIV identification code

RIV/00216224:14110/16:00091178

Organization unit

Faculty of Medicine

ISSN

Keywords in English

brain neuron; Magnetic Resonance Imaging techniques

Tags

Změněno: 12/10/2016 09:50, Ing. Mgr. Věra Pospíšilíková

Abstract

V originále

Objective: In our study, we focus on particular brain neurons and their axonal connections within the brainstem and spinal cord, which regulate the sympathetic and parasympathetic nerves functions, involved in the regulation of blood pressure. Processes of neuromodulation are mentioned to take place within these neural connections of central nervous system. The target group for analysis is represented by patients with hypertension. Design and method: We analysed the descending nervous fascicle in patients with hypertension and in healthy controls. All probands (16 patients with hypertension, 12 healthy controls) of our pilot study underwent the non-invasive, one-time magnetic resonance imaging scanning. For the central nervous system structures mapping, we have used the non-invasive Magnetic Resonance imaging techniques (3T MR system Discovery MR750 GE, software DV24.0_R01_1344.a), combined with specific software processing (Philips working station, MR Diffusion + MR FiberTrack analysis). Received data were analyzed by using statistics (Mann-Whitney test for comparison of parameters between groups). Results: For the oral presentation, the results are presented as very visual MRI - tractography images and clear Gauss curves comparisons too.