J 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

SLANINOVÁ, Iva et. al.

Basic information

Original name

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Authors

SLANINOVÁ, Iva (203 Czech Republic, guarantor, belonging to the institution) et. al.

Edition

Autophagy, Philadelphia, Taylor & Francis INC, 2016, 1554-8627

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 8.593

RIV identification code

RIV/00216224:14110/16:00091235

Organization unit

Faculty of Medicine

DOI

UT WoS

000373595400001

Keywords in English

autolysosome; autophagosome; chaperone-mediated autophagy; flux; LC3; lysosome; macroautophagy; phagophore; stress; vacuole

Tags

Tags

International impact, Reviewed
Změněno: 19/10/2016 10:07, Ing. Mgr. Věra Pospíšilíková

Abstract

V originále

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes.