Detailed Information on Publication Record
2017
Vitamin D receptor TaqI gene polymorphism and dental caries in Czech children
IZAKOVIČOVÁ HOLLÁ, Lydie, Petra BOŘILOVÁ LINHARTOVÁ, Jakub KAŠTOVSKÝ, Michaela BARTOŠOVÁ, Kristína MUSILOVÁ et. al.Basic information
Original name
Vitamin D receptor TaqI gene polymorphism and dental caries in Czech children
Name in Czech
TaqI polymorfizmus v genu pro receptor vitaminu D a zubní kaz u českých dětí
Authors
IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor, belonging to the institution), Petra BOŘILOVÁ LINHARTOVÁ (203 Czech Republic, belonging to the institution), Jakub KAŠTOVSKÝ (203 Czech Republic, belonging to the institution), Michaela BARTOŠOVÁ (703 Slovakia, belonging to the institution), Kristína MUSILOVÁ (203 Czech Republic), Lubomír KUKLA (203 Czech Republic, belonging to the institution) and Martina KUKLETOVÁ (203 Czech Republic)
Edition
Caries Research, Basel, Karger, 2017, 0008-6568
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30208 Dentistry, oral surgery and medicine
Country of publisher
Switzerland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.188
RIV identification code
RIV/00216224:14110/17:00094561
Organization unit
Faculty of Medicine
UT WoS
000395969500003
Keywords in English
case-control study; dental caries; gene polymorphism; Gingivitis; Vitamin D receptor
Tags
International impact, Reviewed
Změněno: 18/3/2018 15:34, Soňa Böhmová
V originále
Aim: We analyzed the VDR TaqI (rs731236) gene polymorphism in children with and those without dental caries. Methods: A total of 388 subjects, 153 caries-free (with decayed/missing/filled teeth [DMFT] = 0) and 235 children with dental caries (DMFT >=1), were genotyped by the TaqMan method. Results: Although no significant differences in VDR TaqI allele and genotype frequencies between caries-free and caries-affected children were detected, a significant association between this polymorphism and gingivitis was found (p < 0.05). Conclusions: In contrast to previous studies from China and Turkey, the VDR TaqI gene variant cannot be used as a marker for identification of Czech children with increased dental caries risk.
In Czech
V práci jsme analyzovali TaqI (rs731236) polymorfizmus v genu pro VDR. Na rozdíl od dřívějších studií z Číny a Turecka, VDR TaqI varianta genu nemůže být využita jako "marker" zvýšeného rizika zubního kazu u českých dětí.
Links
| GB14-37368G, research and development project |
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| MUNI/A/1258/2015, interní kód MU |
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| ROZV/24/LF/2016, interní kód MU |
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