Death due to acute massive pulmonary thromboembolism associated
with risperidone

a 2016

Death due to acute massive pulmonary thromboembolism associated with risperidone

EREN, Filiz, T. Inanir NURSEL, Bulent EREN, Eser BAYRAKTAR, Okan YILDIZ et. al.

Basic information

Original name

Death due to acute massive pulmonary thromboembolism associated with risperidone

Authors

EREN, Filiz, T. Inanir NURSEL, Bulent EREN, Eser BAYRAKTAR, Okan YILDIZ, N. Gundogmus UMIT and Tomáš VOJTÍŠEK

Edition

IALM intersocietal symposium (International Academy of Legal Medicine) Venice, 2016

Other information

Language

Czech

Type of outcome

Konferenční abstrakt

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Změněno: 31/10/2016 22:50, MUDr. Mgr. Bc. Tomáš Vojtíšek, Ph.D.

Abstract

V originále

Risperidone is an antipsychotic drug, used extensively and for this reason many side effects have been reported. Some of them are increased risk of stroke, thrombosis, pulmonary embolism, due to hyperactivation of blood platelets. Pulmonary thromboembolism is a true medical emergency and pulmonary hypertension is rapidly progressive and leads to right heart failure which may be the cause of death. Some antipsychotic agents have been reported as a risk factor for thromboembolism in adult patients with psychiatric disorders. In our case, 38 year-old-woman with psychiatric disorder who got worse in her house died in the hospital. At autopsy, in internal examination, petechial haemorrhages on surface of lungs, conjestion and edema in the section of lungs and raising of thrombus from vessel structures of lung when lung was compressed were observed and there was no macroscopic pathologic finding in the sections of vessels of lower extremities. In chemical analysis, in blood atropine, 37 ng/ml quetiapine, 4 ng/ml risperidone and in urine atropine, quetiapine, risperidone were detected. Death occurred due to acute massive pulmonary thromboembolism was reported. We aimed to discuss this case with autopsy and histopathologic findings, laboratory results in medicolegal literature.

Citovat

EREN, Filiz, T. Inanir NURSEL, Bulent EREN, Eser BAYRAKTAR, Okan YILDIZ, N. Gundogmus UMIT and Tomáš VOJTÍŠEK. Death due to acute massive pulmonary thromboembolism associated with risperidone. In IALM intersocietal symposium (International Academy of Legal Medicine) Venice. 2016.

@proceedings{1358724,
   author = {Eren, Filiz and Nursel, T. Inanir and Eren, Bulent and Bayraktar, Eser and Yildiz, Okan and Umit, N. Gundogmus and Vojtíšek, Tomáš},
   booktitle = {IALM intersocietal symposium (International Academy of Legal Medicine) Venice},
   language = {cze},
   title = {Death due to acute massive pulmonary thromboembolism associated with risperidone},
   year = {2016}
}

TY  - CONF
ID  - 1358724
AU  - Eren, Filiz - Nursel, T. Inanir - Eren, Bulent - Bayraktar, Eser - Yildiz, Okan - Umit, N. Gundogmus - Vojtíšek, Tomáš
PY  - 2016
TI  - Death due to acute massive pulmonary thromboembolism associated with risperidone
N2  - Risperidone is an antipsychotic drug, used extensively and for this reason many side effects have been reported. Some of them are increased risk of stroke, thrombosis, pulmonary embolism, due to hyperactivation of blood platelets. Pulmonary thromboembolism is a true medical emergency and pulmonary hypertension is rapidly progressive and leads to right heart failure which may be the cause of death. Some antipsychotic agents have been reported as a risk factor for thromboembolism in adult patients with psychiatric disorders. In our case, 38 year-old-woman with psychiatric disorder who got worse in her house died in the hospital. At autopsy, in internal examination, petechial haemorrhages on surface of lungs, conjestion and edema in the section of lungs and raising of thrombus from vessel structures of lung when lung was compressed were observed and there was no macroscopic pathologic finding in the sections of vessels of lower extremities. In chemical analysis, in blood atropine, 37 ng/ml quetiapine, 4 ng/ml risperidone and in urine atropine, quetiapine, risperidone were detected. Death occurred due to acute massive pulmonary thromboembolism was reported. We aimed to discuss this case with autopsy and histopathologic findings, laboratory results in medicolegal literature.
ER  -

EREN, Filiz, T. Inanir NURSEL, Bulent EREN, Eser BAYRAKTAR, Okan YILDIZ, N. Gundogmus UMIT and Tomáš VOJTÍŠEK. Death due to acute massive pulmonary thromboembolism associated with risperidone. In \textit{IALM intersocietal symposium (International Academy of Legal Medicine) Venice}. 2016.

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