| KOMINKOVA, Marketa, Vedran MILOSAVLJEVIC, Petr VITEK, Hana POLANSKÁ, Kristyna CIHALOVA, Simona DOSTALOVA, Veronika HYNSTOVA, Roman GURÁŇ, Pavel KOPEL, Lukas RICHTERA, Michal MASAŘÍK, Martin BRTNICKY, Jindrich KYNICKY, Ondrej ZITKA a Vojtech ADAM. Comparative study on toxicity of extracellularly biosynthesized and laboratory synthesized CdTe quantum dots. Journal of Biotechnology. Amsterdam: Elsevier Science BV, 2017, roč. 241, "neuvedeno", s. 193-200. ISSN 0168-1656. Dostupné z: https://dx.doi.org/10.1016/j.jbiotec.2016.10.024. |
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@article{1361907,
author = {Kominkova, Marketa and Milosavljevic, Vedran and Vitek, Petr and Polanská, Hana and Cihalova, Kristyna and Dostalova, Simona and Hynstova, Veronika and Guráň, Roman and Kopel, Pavel and Richtera, Lukas and Masařík, Michal and Brtnicky, Martin and Kynicky, Jindrich and Zitka, Ondrej and Adam, Vojtech},
article_location = {Amsterdam},
article_number = {"neuvedeno"},
doi = {http://dx.doi.org/10.1016/j.jbiotec.2016.10.024},
keywords = {Quantum dots; Biosynthesis; Escherichia coli (E. coli); CdTe; Toxicity},
language = {eng},
issn = {0168-1656},
journal = {Journal of Biotechnology},
title = {Comparative study on toxicity of extracellularly biosynthesized and laboratory synthesized CdTe quantum dots},
url = {http://dx.doi.org/10.1016/j.jbiotec.2016.10.024},
volume = {241},
year = {2017}
}
TY - JOUR
ID - 1361907
AU - Kominkova, Marketa - Milosavljevic, Vedran - Vitek, Petr - Polanská, Hana - Cihalova, Kristyna - Dostalova, Simona - Hynstova, Veronika - Guráň, Roman - Kopel, Pavel - Richtera, Lukas - Masařík, Michal - Brtnicky, Martin - Kynicky, Jindrich - Zitka, Ondrej - Adam, Vojtech
PY - 2017
TI - Comparative study on toxicity of extracellularly biosynthesized and laboratory synthesized CdTe quantum dots
JF - Journal of Biotechnology
VL - 241
IS - "neuvedeno"
SP - 193-200
EP - 193-200
PB - Elsevier Science BV
SN - 01681656
KW - Quantum dots
KW - Biosynthesis
KW - Escherichia coli (E. coli)
KW - CdTe
KW - Toxicity
UR - http://dx.doi.org/10.1016/j.jbiotec.2016.10.024
N2 - Nanobiosynthesis belongs to the most recent methods for synthesis of nanoparticles. This type of synthesis provides many advantages including the uniformity in particle shape and size. The biosynthesis has also a significant advantage regarding chemical properties of the obtained particles. In this study, we characterized the basic properties and composition of quantum dots (QDs), obtained by the extracellular biosynthesis by Escherichia coli. Furthermore, the toxicity of the biosynthesized QDs was compared to QDs prepared by microwave synthesis. The obtained results revealed the presence of cyan CdTe QDs after removal of substantial amounts of organic compounds, which stabilized the nanoparticle surface. QDs toxicity was evaluated using three cell lines Human Foreskin Fibroblast (HFF), Human Prostate Cancer cells (PC-3) and Breast Cancer cells (MCF-7) and the MTT assay. The test revealed differences in the toxicity between variants of QDs, varying about 10% in the HFF and 30% in the MCF-7 cell lines. The toxicity of the biosynthesized QDs to the PC-3 cell lines was about 35% lower in comparison with the QDs prepared by microwave synthesis.
ER -
KOMINKOVA, Marketa, Vedran MILOSAVLJEVIC, Petr VITEK, Hana POLANSKÁ, Kristyna CIHALOVA, Simona DOSTALOVA, Veronika HYNSTOVA, Roman GURÁŇ, Pavel KOPEL, Lukas RICHTERA, Michal MASAŘÍK, Martin BRTNICKY, Jindrich KYNICKY, Ondrej ZITKA a Vojtech ADAM. Comparative study on toxicity of extracellularly biosynthesized and laboratory synthesized CdTe quantum dots. \textit{Journal of Biotechnology}. Amsterdam: Elsevier Science BV, 2017, roč.~241, ''neuvedeno'', s.~193-200. ISSN~0168-1656. Dostupné z: https://dx.doi.org/10.1016/j.jbiotec.2016.10.024.
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