EN

Sequential Hybrid CryoMaze Ablation versus Surgical CryoMaze Alone for the Treatment of Atrial ...

EISENBERGER, Martin, Alan BULAVA, Josef KAUTZNER, Petr NEUZIL, Ales MOKRACEK, Jiri HANIS a Ladislav DUŠEK. Sequential Hybrid CryoMaze Ablation versus Surgical CryoMaze Alone for the Treatment of Atrial Fibrillation (SurHyb): study protocol for a randomized controlled trial. Trials, London: BioMed Central, 2016, roč. 17, č. 518, s. 1-7. ISSN 1745-6215. doi:10.1186/s13063-016-1634-4.
Další formáty:   BibTeX LaTeX RIS
Základní údaje
Originální název Sequential Hybrid CryoMaze Ablation versus Surgical CryoMaze Alone for the Treatment of Atrial Fibrillation (SurHyb): study protocol for a randomized controlled trial
Autoři EISENBERGER, Martin (203 Česká republika), Alan BULAVA (203 Česká republika), Josef KAUTZNER (203 Česká republika), Petr NEUZIL (203 Česká republika), Ales MOKRACEK (203 Česká republika), Jiri HANIS (203 Česká republika) a Ladislav DUŠEK (203 Česká republika, garant, domácí).
Vydání Trials, London, BioMed Central, 2016, 1745-6215.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor Cardiac and Cardiovascular systems
Stát vydavatele Spojené království
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 1.969
Kód RIV RIV/00216224:14110/16:00092164
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1186/s13063-016-1634-4
UT WoS 000386077600003
Klíčová slova anglicky Atrial fibrillation; Catheter ablation; Surgical ablation; CryoMaze; Randomized controlled clinical trial; Hybrid approach
Štítky EL OK
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Ing. Mgr. Věra Pospíšilíková, učo 9005. Změněno: 6. 12. 2016 12:27.
Anotace
Background: Atrial fibrillation is common in patients with structural heart disease who are undergoing cardiac surgery. Surgical CryoMaze has been shown to be an effective treatment in several trials, but success rates have varied considerably, between 47-95 %. The sequential hybrid approach, combining surgical CryoMaze followed by radiofrequency catheter ablation, can achieve high freedom from atrial arrhythmias, even when rigorous methods to detect arrhythmias after the procedure are used. However, data from randomized trials comparing hybrid ablations to surgical ablations alone are lacking. Methods/Design: The SurHyb study is a prospective, multicenter, randomized study. Patients with persistent or long-standing persistent atrial fibrillation will be randomized to either surgical CryoMaze alone or surgical CryoMaze followed by catheter ablation 3 months post-surgery. The primary outcome measure is arrhythmia-free survival without class I or III antiarrhythmic drugs, which will be evaluated using 7-day ECG Holter monitoring at 24 months. A total of 260 patients will be investigated from three medical centers in the Czech Republic to obtain the relevant information. Discussion: This is the first randomized study that compares surgical CryoMaze alone with the staged hybrid surgical CryoMaze followed by catheter ablation in patients with persistent or long-standing persistent atrial fibrillation. These results will contribute to the optimization of the treatment for these patients.
VytisknoutZobrazeno: 20. 4. 2019 22:36

Další aplikace