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@proceedings{1363910,
author = {Nevídalová, Hana and Michalcová, Lenka and Glatz, Zdeněk},
booktitle = {31st International Symposium on Chromatography (ISC2016},
keywords = {drug-protein interaction, diclofenac, albumin},
language = {eng},
title = {Comparison of different methodologies – capillary electrophoresis - frontal analysis, equilibrium dialysis, circular dichroism and isothermal titration calorimetry for studying drug-protein interactions},
url = {http://www.isc2016.ie/},
year = {2016}
}
TY - CONF
ID - 1363910
AU - Nevídalová, Hana - Michalcová, Lenka - Glatz, Zdeněk
PY - 2016
TI - Comparison of different methodologies – capillary electrophoresis - frontal analysis, equilibrium dialysis, circular dichroism and isothermal titration calorimetry for studying drug-protein interactions
KW - drug-protein interaction, diclofenac, albumin
UR - http://www.isc2016.ie/
N2 - Pharmacokinetics and pharmacodynamics behaviour of drug is influenced by its binding on human serum albumin. Therefore the evaluation of analytical methods for analysis of these interactions with a small amount of sample solution is a highly desirable.Integrating benefit of these methodologies is possibility to measure interaction of binding partners in their native states without immobilization or labelling under physiological conditions.
ER -
NEVÍDALOVÁ, Hana, Lenka MICHALCOVÁ a Zdeněk GLATZ. Comparison of different methodologies – capillary electrophoresis - frontal analysis, equilibrium dialysis, circular dichroism and isothermal titration calorimetry for studying drug-protein interactions. In \textit{31st International Symposium on Chromatography (ISC2016}. 2016.
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