CUNDRLE JR., Ivan, Milos BELEHRAD, Milan JELINEK, Lyle J. OLSON, Ondřej LUDKA and Vladimir SRAMEK. The utility of perioperative polygraphy in the diagnosis of obstructive sleep apnea. Sleep Medicine. Amsterdam: Elsevier Science BV, 2016, vol. 25, "neuvedeno", p. 151-155. ISSN 1389-9457. Available from: https://dx.doi.org/10.1016/j.sleep.2016.03.009.
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Basic information
Original name The utility of perioperative polygraphy in the diagnosis of obstructive sleep apnea
Authors CUNDRLE JR., Ivan (203 Czech Republic), Milos BELEHRAD (203 Czech Republic), Milan JELINEK (203 Czech Republic), Lyle J. OLSON (840 United States of America), Ondřej LUDKA (203 Czech Republic, guarantor, belonging to the institution) and Vladimir SRAMEK (203 Czech Republic).
Edition Sleep Medicine, Amsterdam, Elsevier Science BV, 2016, 1389-9457.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.391
RIV identification code RIV/00216224:14110/16:00092285
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.sleep.2016.03.009
UT WoS 000389112500025
Keywords in English Obstructive sleep apnea; Sleep-disordered breathing; Screening; Sedation
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 9/1/2017 17:04.
Abstract
Objective/Background: Obstructive sleep apnea (OSA) is highly prevalent and often undiagnosed in surgical patients. The aim of this study was to compare polygraphy (PG) performed on sedated patients during surgery to overnight polysomnography (PSG). It was hypothesized that perioperative PG may be used to diagnose OSA. Patients/Methods: Overnight PSG was performed three days prior to surgery. For surgery, spinal anesthesia and sedation with propofol infusion were used. Sedation depth was monitored by the Bispectral index and maintained for all patients (target level 75). Echocardiography studies were available in three patients, and all were diagnosed with diastolic dysfunction. Relatively high prevalence of CSA in patients with diastolic dysfunction has been previously reported. During surgery, PG recording (Embletta) was performed. Sleep apnea was defined by the type (central/obstructive apnea >= 50%) and by the apneahypopnea index (AHI) (events/hour: AHI < 5 no apnea; 5 <= AHI < 15 mild apnea; 15 <= AHI <30 moderate apnea; AHI 30 severe apnea). Bland-Altman plots were used for analysis, and 2 x 2 decision statistics were calculated for several cut-off values of the AHI. Data were shown as bias with limits of agreement (bias +/- 1.96 standard deviations). Results: Nineteen subjects were studied: nine (47%) were diagnosed with obstructive, seven (37%) with central sleep apnea, and three (16%) with no sleep apnea by overnight PSG. Perioperative PG bias was 12 (-37; 61) for AHI; 6 (-25; 37) for obstructive apnea; 0 (-4; 4) for central apnea, and 6 (-31; 43) for hypopnea. For the detection of OSA, a PG cut-off value of AHI 5 yielded 89% sensitivity and 60% specificity, AHI 15 yielded 86% sensitivity and 67% specificity, and AHI 30 yielded 100% sensitivity and 71% specificity. Conclusion: Wide limits of agreement preclude perioperative PG to be used as a diagnostic method; however, it may be useful to screen sedated surgical patients for OSA.
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