e 2016

Fibrous Dysplasia Presenting as a Cold Spot in F-18-FLT PET/CT Imaging

ŘEHÁK, Zdeněk, Beatrix BENCSIKOVA, Iva ZAMBO and Tomáš KAZDA

Basic information

Original name

Fibrous Dysplasia Presenting as a Cold Spot in F-18-FLT PET/CT Imaging

Authors

ŘEHÁK, Zdeněk (203 Czech Republic, guarantor, belonging to the institution), Beatrix BENCSIKOVA (203 Czech Republic), Iva ZAMBO (203 Czech Republic, belonging to the institution) and Tomáš KAZDA (203 Czech Republic, belonging to the institution)

Edition

Philadelphia, 2016

Publisher

Lippincott Williams & Wilkins

Other information

Language

English

Type of outcome

Přehledové a vzdělávací texty

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.563

RIV identification code

RIV/00216224:14110/16:00092297

Organization unit

Faculty of Medicine

ISSN

DOI

UT WoS

000376886800039

Keywords in English

fibrous dysplasia; FLT; thymidine; PET/CT; bone tumor

Tags

Změněno: 13/12/2016 11:17, Ing. Mgr. Věra Pospíšilíková

Abstract

V originále

Fibrous dysplasia (FD) is a benign bone lesion in which normal bone marrow is replaced by fibro-osseous tissue. The usual high fluorodeoxyglucose (F-18-FDG) uptake in FD may lead to the misdiagnosis of bone malignancy. Herein, we describe the case of a 42-year old man with histologically verified FD of the pubic bone, which has been subsequently examined during follow-up for rectal cancer, using both F-18-FDG and fluorothymidine (F-18-FLT) PET/CT imaging. The FD lesion was characterized by a high uptake of F-18-FDG (hot spot) but very low uptake of F-18-FLT (cold spot) as compared with the contralateral unaffected pubic bone.