J 2016

High-Frequency Oscillations in the Human Anterior Nucleus of the Thalamus

REKTOR, Ivan, Irena DOLEŽALOVÁ, Jan CHRASTINA, Pavel JURÁK, Josef HALÁMEK et. al.

Basic information

Original name

High-Frequency Oscillations in the Human Anterior Nucleus of the Thalamus

Authors

REKTOR, Ivan (203 Czech Republic, guarantor, belonging to the institution), Irena DOLEŽALOVÁ (203 Czech Republic, belonging to the institution), Jan CHRASTINA (203 Czech Republic, belonging to the institution), Pavel JURÁK (203 Czech Republic), Josef HALÁMEK (203 Czech Republic), Marek BALÁŽ (703 Slovakia, belonging to the institution) and Milan BRÁZDIL (203 Czech Republic, belonging to the institution)

Edition

BRAIN STIMULATION, NEW YORK, ELSEVIER SCIENCE INC, 2016, 1935-861X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 6.078

RIV identification code

RIV/00216224:14740/16:00092337

Organization unit

Central European Institute of Technology

UT WoS

000378063000023

Keywords in English

ELECTRICAL-STIMULATION; EPILEPSY

Tags

Změněno: 15/12/2016 09:55, Mgr. Eva Špillingová

Abstract

V originále

Deep brain stimulation of the anterior nucleus of the thalamus (ANT- DBS) has recently been introduced in therapy for refractory epilepsy and is approved for clinical use in Europe. ANT is a part of the Papez circuitry and is a key structure in the intrathalamic pathways; it also projects to the cingulate gyrus and further to the limbic structures and wide regions of the neocortex, and via the mammillary circuit to the brain stem. ANT stimulation produces EEG changes in the frontal and temporal areas and inhibits seizures. The role played by the ANT in human epileptic seizures and the mechanisms leading to the anti- seizure effects of ANT-DBS have not yet been fully elucidated. Knowledge of processes occurring in the ANT in human epilepsy might improve the understanding of its role. Here we report the first description of interictal and ictal EEG recording in the human ANT.

Links

LQ1601, research and development project
Name: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR