Detailed Information on Publication Record
2016
Calculating Stress: From Entropy to a Thermodynamic Concept of Health and Disease
BIENERTOVÁ VAŠKŮ, Julie, Filip ZLÁMAL, Ivo NEČESÁNEK, David KONEČNÝ, Anna VAŠKŮ et. al.Basic information
Original name
Calculating Stress: From Entropy to a Thermodynamic Concept of Health and Disease
Authors
BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor, belonging to the institution), Filip ZLÁMAL (203 Czech Republic, belonging to the institution), Ivo NEČESÁNEK (203 Czech Republic, belonging to the institution), David KONEČNÝ (203 Czech Republic, belonging to the institution) and Anna VAŠKŮ (203 Czech Republic, belonging to the institution)
Edition
Plos one, San Francisco, Public Library of Science, 2016, 1932-6203
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30105 Physiology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.806
RIV identification code
RIV/00216224:14110/16:00092415
Organization unit
Faculty of Medicine
UT WoS
000368628300028
Keywords in English
Calculating Stress
Tags
Tags
International impact, Reviewed
Změněno: 19/12/2016 12:22, Soňa Böhmová
Abstract
V originále
To date, contemporary science has lacked a satisfactory tool for the objective expression of stress. This text thus introduces a new-thermodynamically derived-approach to stress measurement, based on entropy production in time and independent of the quality or modality of a given stressor or a combination thereof. Hereto, we propose a novel model of stress response based on thermodynamic modelling of entropy production, both in the tissues/organs and in regulatory feedbacks. Stress response is expressed in our model on the basis of stress entropic load (SEL), a variable we introduced previously; the mathematical expression of SEL, provided here for the first time, now allows us to describe the various states of a living system, including differentiating between states of health and disease. The resulting calculation of stress response regardless of the type of stressor(s) in question is thus poised to become an entirely new tool for predicting the development of a living system.