J 2016

Calculating Stress: From Entropy to a Thermodynamic Concept of Health and Disease

BIENERTOVÁ VAŠKŮ, Julie, Filip ZLÁMAL, Ivo NEČESÁNEK, David KONEČNÝ, Anna VAŠKŮ et. al.

Basic information

Original name

Calculating Stress: From Entropy to a Thermodynamic Concept of Health and Disease

Authors

BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor, belonging to the institution), Filip ZLÁMAL (203 Czech Republic, belonging to the institution), Ivo NEČESÁNEK (203 Czech Republic, belonging to the institution), David KONEČNÝ (203 Czech Republic, belonging to the institution) and Anna VAŠKŮ (203 Czech Republic, belonging to the institution)

Edition

Plos one, San Francisco, Public Library of Science, 2016, 1932-6203

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.806

RIV identification code

RIV/00216224:14110/16:00092415

Organization unit

Faculty of Medicine

UT WoS

000368628300028

Keywords in English

Calculating Stress

Tags

Tags

International impact, Reviewed
Změněno: 19/12/2016 12:22, Soňa Böhmová

Abstract

V originále

To date, contemporary science has lacked a satisfactory tool for the objective expression of stress. This text thus introduces a new-thermodynamically derived-approach to stress measurement, based on entropy production in time and independent of the quality or modality of a given stressor or a combination thereof. Hereto, we propose a novel model of stress response based on thermodynamic modelling of entropy production, both in the tissues/organs and in regulatory feedbacks. Stress response is expressed in our model on the basis of stress entropic load (SEL), a variable we introduced previously; the mathematical expression of SEL, provided here for the first time, now allows us to describe the various states of a living system, including differentiating between states of health and disease. The resulting calculation of stress response regardless of the type of stressor(s) in question is thus poised to become an entirely new tool for predicting the development of a living system.