BIENERTOVÁ VAŠKŮ, Julie, Filip ZLÁMAL, Ivo NEČESÁNEK, David KONEČNÝ and Anna VAŠKŮ. Calculating Stress: From Entropy to a Thermodynamic Concept of Health and Disease. Plos one. San Francisco: Public Library of Science, 2016, vol. 11, No 1, p. "e0146667", 13 pp. ISSN 1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0146667.
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Basic information
Original name Calculating Stress: From Entropy to a Thermodynamic Concept of Health and Disease
Authors BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor, belonging to the institution), Filip ZLÁMAL (203 Czech Republic, belonging to the institution), Ivo NEČESÁNEK (203 Czech Republic, belonging to the institution), David KONEČNÝ (203 Czech Republic, belonging to the institution) and Anna VAŠKŮ (203 Czech Republic, belonging to the institution).
Edition Plos one, San Francisco, Public Library of Science, 2016, 1932-6203.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30105 Physiology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.806
RIV identification code RIV/00216224:14110/16:00092415
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1371/journal.pone.0146667
UT WoS 000368628300028
Keywords in English Calculating Stress
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 19/12/2016 12:22.
Abstract
To date, contemporary science has lacked a satisfactory tool for the objective expression of stress. This text thus introduces a new-thermodynamically derived-approach to stress measurement, based on entropy production in time and independent of the quality or modality of a given stressor or a combination thereof. Hereto, we propose a novel model of stress response based on thermodynamic modelling of entropy production, both in the tissues/organs and in regulatory feedbacks. Stress response is expressed in our model on the basis of stress entropic load (SEL), a variable we introduced previously; the mathematical expression of SEL, provided here for the first time, now allows us to describe the various states of a living system, including differentiating between states of health and disease. The resulting calculation of stress response regardless of the type of stressor(s) in question is thus poised to become an entirely new tool for predicting the development of a living system.
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