J 2017

Single-Phase Versus Multiphase CT Angiography in Middle Cerebral Artery Clot Detection-Benefits for Less Experienced Radiologists and Neurologists

VOLNÝ, Ondřej, Petra CIMFLOVÁ, Pavla KADLECOVA, Petr VANĚK, Jiří VANÍČEK et. al.

Basic information

Original name

Single-Phase Versus Multiphase CT Angiography in Middle Cerebral Artery Clot Detection-Benefits for Less Experienced Radiologists and Neurologists

Authors

VOLNÝ, Ondřej (203 Czech Republic, belonging to the institution), Petra CIMFLOVÁ (203 Czech Republic, belonging to the institution), Pavla KADLECOVA (203 Czech Republic), Petr VANĚK (203 Czech Republic, belonging to the institution), Jiří VANÍČEK (203 Czech Republic, belonging to the institution), Bijoy K. MENON (124 Canada) and Robert MIKULÍK (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Stroke & Cerebrovascular Diseases, Amsterdam, Elsevier Science Inc. 2017, 1052-3057

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.598

RIV identification code

RIV/00216224:14110/17:00095976

Organization unit

Faculty of Medicine

DOI

UT WoS

000396430100013

Keywords in English

Acute stroke; CT angiography; Distal clot; Middle cerebral artery; Multiphase CTA

Tags

Tags

International impact, Reviewed
Změněno: 20/3/2018 11:46, Soňa Böhmová

Abstract

V originále

Objectives: CT angiography (CTA) is recommended as a standard of stroke imaging. We investigated accuracy and precision of standard or single-phase CTA as compared with novel technique or multiphase CTA in clot detection in the middle cerebral artery. Methods: Twenty single-phase CTA and twenty multiphase CTA with prevailing M2 occlusion were assessed by 10 radiologists and 10 neurologists blinded to clinical information (7 less experienced and 3 experienced). Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated as compared with reading by two seniors. Reliability was calculated using Krippendorff's alpha (K-alpha). Results: Sensitivity, specificity, PPV, and NPV of single-phase CTA compared with multiphase CTA for M2 clot presence were, respectively, .86, .75, .90, and .67 versus .88, .82, .92, and .72. For secondary or distal clots, sensitivity, specificity, PPV, and NPV of single-phase CTA compared with multiphase CTA were .41, .83, .50, and .78 versus .65, .77, .71, and .67. Agreement increased significantly in favor of multiphase CTA for detection of primary clots from moderate (.43) to substantial (.65) in less experienced radiologists and from slight (.10) to moderate (.30) in less experienced neurologists. Agreement significantly increased for distal or secondary clot detection in favor of multiphase CTA from fair (.24) to moderate (.49) in experienced radiologists and from slight (.12) to moderate (.46) in experienced neurologists. Conclusions: Multiphase CTA is a reliable imaging tool in M2 clot detection and might represent a beneficial imaging tool in clot detection for less experienced physicians.