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@article{1366194,
author = {Hrabovský, Dušan and Baláž, Marek and Rab, M. and Feitová, Věra and Hummelová, Zuzana and Novák, Zdeněk and Chrastina, Jan},
article_location = {Abingdon},
article_number = {2},
doi = {http://dx.doi.org/10.1080/02688697.2016.1226256},
keywords = {Deep brain stimulation; Parkinson’s disease; subthalamic nucleus; early postoperative mental changes; brain atrophy},
language = {eng},
issn = {0268-8697},
journal = {British Journal of Neurosurgery},
title = {Factors responsible for early postoperative mental alterations after bilateral implantation of subthalamic electrodes},
volume = {31},
year = {2017}
}
TY - JOUR
ID - 1366194
AU - Hrabovský, Dušan - Baláž, Marek - Rab, M. - Feitová, Věra - Hummelová, Zuzana - Novák, Zdeněk - Chrastina, Jan
PY - 2017
TI - Factors responsible for early postoperative mental alterations after bilateral implantation of subthalamic electrodes
JF - British Journal of Neurosurgery
VL - 31
IS - 2
SP - 212-216
EP - 212-216
PB - Taylor & Francis LTD
SN - 02688697
KW - Deep brain stimulation
KW - Parkinson’s disease
KW - subthalamic nucleus
KW - early postoperative mental changes
KW - brain atrophy
N2 - Introduction: Early postoperative mental changes are the most frequent problem after bilateral subthalamic electrode implantation. The study aims to find an association between them and factors related to patient, disease and surgery, including the size of the third ventricle as brain atrophy marker. Material and methods: The study included 80 patients with bilateral subthalamic electrodes implanted for motor complications of Parkinson’s disease (PD). Patients’ age, disease and motor complications duration, medication, neuropsychological tests, surgical reports, third ventricle length (intercommissural distance) and width (intermammillary distance) were analysed. Results: Early mental alterations requiring treatment were observed in 25.0% of patients with higher age being significant predictor. The duration of PD motor complications, L DOPA equivalent dose, DSR Mattis, third ventricle length and width were not statistically significant predictors. The incidence of postoperative mental alteration with intermammillary distance > 8 mm was 60%. The percentage of left sided electrodes implanted in anterior trajectory is significantly higher in patients with early mental changes. Conclusions: Higher age is a risk factor for early postoperative mental changes, but not disease, late motor complications duration and parameters describing third ventricular size except the excessive intermammillary distance. Left sided electrode implanted in anterior position is a risk factor.
ER -
HRABOVSKÝ, Dušan, Marek BALÁŽ, M. RAB, Věra FEITOVÁ, Zuzana HUMMELOVÁ, Zdeněk NOVÁK and Jan CHRASTINA. Factors responsible for early postoperative mental alterations after bilateral implantation of subthalamic electrodes. \textit{British Journal of Neurosurgery}. Abingdon: Taylor \&{} Francis LTD, 2017, vol.~31, No~2, p.~212-216. ISSN~0268-8697. Available from: https://dx.doi.org/10.1080/02688697.2016.1226256.
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