Motion and emotion: anxiety-axial connections in Parkinson's
disease

J 2017

Motion and emotion: anxiety-axial connections in Parkinson's disease

ŠUMEC, Rastislav, Irena REKTOROVÁ, Robert JECH, Kateřina MENŠÍKOVÁ, Jan ROTH et. al.

Basic information

Original name

Motion and emotion: anxiety-axial connections in Parkinson's disease

Authors

ŠUMEC, Rastislav (703 Slovakia, belonging to the institution), Irena REKTOROVÁ (203 Czech Republic, belonging to the institution), Robert JECH (203 Czech Republic), Kateřina MENŠÍKOVÁ (203 Czech Republic), Jan ROTH (203 Czech Republic), Evžen RŮŽIČKA (203 Czech Republic), Dana SOCHOROVÁ (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Petr KAŇOVSKÝ (203 Czech Republic), Ivan REKTOR (203 Czech Republic, belonging to the institution), Tomáš PAVLÍK (203 Czech Republic, belonging to the institution), Pavel FILIP (703 Slovakia, belonging to the institution) and Martin BAREŠ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Neural Transmission, Wien, Springer Wien, 2017, 0300-9564

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

Austria

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.779

RIV identification code

RIV/00216224:14110/17:00095993

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s00702-016-1652-0

UT WoS

000394433100009

Keywords in English

Anxiety; Instability; Mood; Parkinson’s disease; Posture

Abstract

V originále

Anxiety is a serious and frequent complication in Parkinson’s disease (PD) that significantly affects the quality of life of patients. Multiple neuroanatomical, experimental, and clinical studies suggest its close association with axial disturbances. However, whether this relation applies for PD patients (commonly suffering from axial difficulties, such as balance and gait disturbance) has not been properly tested yet. The purpose of this study was to determine whether PD patients suffering from axial symptoms have higher levels of anxiety than others and to identify other factors associated with anxiety–axial connections. In this questionnaire study, 212 patients with PD were assessed by standardized scales, such as Hamilton Anxiety Scale, Montgomery–Asberg Depression Rating Scale, Montreal Cognitive Assessment, examining their mood and cognitive status. These data were correlated to dominant motor symptoms of these patients, such as tremor, rigidity, bradykinesia, and axial symptoms. Unlike other motor symptoms, only axial symptoms showed to be significantly related to higher levels of anxiety. The patients suffering from anxiety and axial problems have also shown significantly higher depression levels. Axial disturbances are related to higher anxiety levels in PD patients. It is crucial to pay high attention to symptoms of anxiety in patients having postural instability or gait disorder. Further clinical studies are desirable to investigate new, practical implications of anxiety–axial connection to provide complex management options of these serious symptoms.

Links

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

ŠUMEC, Rastislav, Irena REKTOROVÁ, Robert JECH, Kateřina MENŠÍKOVÁ, Jan ROTH, Evžen RŮŽIČKA, Dana SOCHOROVÁ, Ladislav DUŠEK, Petr KAŇOVSKÝ, Ivan REKTOR, Tomáš PAVLÍK, Pavel FILIP and Martin BAREŠ. Motion and emotion: anxiety-axial connections in Parkinson's disease. Journal of Neural Transmission. Wien: Springer Wien, 2017, vol. 124, No 3, p. 369-377. ISSN 0300-9564. Available from: https://dx.doi.org/10.1007/s00702-016-1652-0.

@article{1366506,
   author = {Šumec, Rastislav and Rektorová, Irena and Jech, Robert and Menšíková, Kateřina and Roth, Jan and Růžička, Evžen and Sochorová, Dana and Dušek, Ladislav and Kaňovský, Petr and Rektor, Ivan and Pavlík, Tomáš and Filip, Pavel and Bareš, Martin},
   article_location = {Wien},
   article_number = {3},
   doi = {http://dx.doi.org/10.1007/s00702-016-1652-0},
   keywords = {Anxiety; Instability; Mood; Parkinson’s disease; Posture},
   language = {eng},
   issn = {0300-9564},
   journal = {Journal of Neural Transmission},
   title = {Motion and emotion: anxiety-axial connections in Parkinson's disease},
   volume = {124},
   year = {2017}
}

TY  - JOUR
ID  - 1366506
AU  - Šumec, Rastislav - Rektorová, Irena - Jech, Robert - Menšíková, Kateřina - Roth, Jan - Růžička, Evžen - Sochorová, Dana - Dušek, Ladislav - Kaňovský, Petr - Rektor, Ivan - Pavlík, Tomáš - Filip, Pavel - Bareš, Martin
PY  - 2017
TI  - Motion and emotion: anxiety-axial connections in Parkinson's disease
JF  - Journal of Neural Transmission
VL  - 124
IS  - 3
SP  - 369-377
EP  - 369-377
PB  - Springer Wien
SN  - 03009564
KW  - Anxiety
KW  - Instability
KW  - Mood
KW  - Parkinson’s disease
KW  - Posture
N2  - Anxiety is a serious and frequent complication in Parkinson’s disease (PD) that significantly affects the quality of life of patients. Multiple neuroanatomical, experimental, and clinical studies suggest its close association with axial disturbances. However, whether this relation applies for PD patients (commonly suffering from axial difficulties, such as balance and gait disturbance) has not been properly tested yet. The purpose of this study was to determine whether PD patients suffering from axial symptoms have higher levels of anxiety than others and to identify other factors associated with anxiety–axial connections. In this questionnaire study, 212 patients with PD were assessed by standardized scales, such as Hamilton Anxiety Scale, Montgomery–Asberg Depression Rating Scale, Montreal Cognitive Assessment, examining their mood and cognitive status. These data were correlated to dominant motor symptoms of these patients, such as tremor, rigidity, bradykinesia, and axial symptoms. Unlike other motor symptoms, only axial symptoms showed to be significantly related to higher levels of anxiety. The patients suffering from anxiety and axial problems have also shown significantly higher depression levels. Axial disturbances are related to higher anxiety levels in PD patients. It is crucial to pay high attention to symptoms of anxiety in patients having postural instability or gait disorder. Further clinical studies are desirable to investigate new, practical implications of anxiety–axial connection to provide complex management options of these serious symptoms.
ER  -

ŠUMEC, Rastislav, Irena REKTOROVÁ, Robert JECH, Kateřina MENŠÍKOVÁ, Jan ROTH, Evžen RŮŽIČKA, Dana SOCHOROVÁ, Ladislav DUŠEK, Petr KAŇOVSKÝ, Ivan REKTOR, Tomáš PAVLÍK, Pavel FILIP and Martin BAREŠ. Motion and emotion: anxiety-axial connections in Parkinson's disease. \textit{Journal of Neural Transmission}. Wien: Springer Wien, 2017, vol.~124, No~3, p.~369-377. ISSN~0300-9564. Available from: https://dx.doi.org/10.1007/s00702-016-1652-0.

Detailed Information on Publication Record