A Thermographic Comparison of Irreversible Electroporation and
Radiofrequency Ablation

J 2017

A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation

BERNARD, Vladan, Tomáš ANDRAŠINA, D. ČERVINKA, J. MARTIŠ, P. PROCHÁZKA et. al.

Basic information

Original name

A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation

Name in Czech

Termografické srovnání radiofrekvenční ablace a irreverzibilní elektroporace

Authors

BERNARD, Vladan (203 Czech Republic, guarantor, belonging to the institution), Tomáš ANDRAŠINA (703 Slovakia), D. ČERVINKA (203 Czech Republic), J. MARTIŠ (203 Czech Republic), P. PROCHÁZKA (203 Czech Republic), Vojtěch MORNSTEIN (203 Czech Republic, belonging to the institution) and Vlastimil VÁLEK (203 Czech Republic)

Edition

IRBM, New York, Elsevier Science INC. 2017, 1959-0318

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

20601 Medical engineering

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.897

RIV identification code

RIV/00216224:14110/17:00095628

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.irbm.2016.11.001

UT WoS

000398761500004

Keywords in English

Balloon catheter; Heating effect; Infrared camera; Irreversible electroporation; Radiofrequency ablation; Temperature

Abstract

V originále

Radiofrequency ablation and irreversible electroporation are both interventional procedures used in treating cancer diseases generally and may be used in treatment of liver cancer. The two differ in terms of their action and thermal effects. The present study examined thermal effects of radiofrequency ablation and modified irreversible electroporation ex vivo in porcine liver. Standard radiofrequency ablation was used during the experiments, as was a unique, experimental high-voltage generator of the research team's own construction coupled with a newly designed balloon electrode catheter for irreversible electroporation. The tested balloon catheter was newly designed for application in the biliary tract. The temperature of porcine liver tissue was monitored without contact by infrared camera. The results show significantly different temperature of tissue around electrodes for radiofrequency ablation and irreversible electroporation. The data obtained from radiofrequency ablation with maximum tested output power of 10 watts show a symmetrical area of tissue near active electrodes with temperature increased by more than 30 C. Irreversible electroporation methods showed temperature increasing approximately by 5 C. To summarize, the thermal research showed that the difference between standard RFA and innovated IRE with the balloon catheter lies not just in the differing mechanism of action, as is well known, but also in its thermal effects. There was documented that tissue temperature was much higher for RFA than for IRE, particularly for the maximum tested output parameters. The applicability of the newly designed balloon catheters was confirmed.

Links

NV15-32484A, research and development project

Name: Využití nových biotechnologií v prevenci a léčbě stenóz žlučových cest

Citovat

BERNARD, Vladan, Tomáš ANDRAŠINA, D. ČERVINKA, J. MARTIŠ, P. PROCHÁZKA, Vojtěch MORNSTEIN and Vlastimil VÁLEK. A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation. IRBM. New York: Elsevier Science INC., 2017, vol. 38, No 1, p. 26-33. ISSN 1959-0318. Available from: https://dx.doi.org/10.1016/j.irbm.2016.11.001.

@article{1367514,
   author = {Bernard, Vladan and Andrašina, Tomáš and Červinka, D. and Martiš, J. and Procházka, P. and Mornstein, Vojtěch and Válek, Vlastimil},
   article_location = {New York},
   article_number = {1},
   doi = {http://dx.doi.org/10.1016/j.irbm.2016.11.001},
   keywords = {Balloon catheter; Heating effect; Infrared camera; Irreversible electroporation; Radiofrequency ablation; Temperature},
   language = {eng},
   issn = {1959-0318},
   journal = {IRBM},
   title = {A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation},
   volume = {38},
   year = {2017}
}

TY  - JOUR
ID  - 1367514
AU  - Bernard, Vladan - Andrašina, Tomáš - Červinka, D. - Martiš, J. - Procházka, P. - Mornstein, Vojtěch - Válek, Vlastimil
PY  - 2017
TI  - A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation
JF  - IRBM
VL  - 38
IS  - 1
SP  - 26-33
EP  - 26-33
PB  - Elsevier Science INC.
SN  - 19590318
KW  - Balloon catheter
KW  - Heating effect
KW  - Infrared camera
KW  - Irreversible electroporation
KW  - Radiofrequency ablation
KW  - Temperature
N2  - Radiofrequency ablation and irreversible electroporation are both interventional procedures used in treating cancer diseases generally and may be used in treatment of liver cancer. The two differ in terms of their action and thermal effects. The present study examined thermal effects of radiofrequency ablation and modified irreversible electroporation ex vivo in porcine liver. Standard radiofrequency ablation was used during the experiments, as was a unique, experimental high-voltage generator of the research team's own construction coupled with a newly designed balloon electrode catheter for irreversible electroporation. The tested balloon catheter was newly designed for application in the biliary tract. The temperature of porcine liver tissue was monitored without contact by infrared camera. The results show significantly different temperature of tissue around electrodes for radiofrequency ablation and irreversible electroporation. The data obtained from radiofrequency ablation with maximum tested output power of 10 watts show a symmetrical area of tissue near active electrodes with temperature increased by more than 30 C. Irreversible electroporation methods showed temperature increasing approximately by 5 C. To summarize, the thermal research showed that the difference between standard RFA and innovated IRE with the balloon catheter lies not just in the differing mechanism of action, as is well known, but also in its thermal effects. There was documented that tissue temperature was much higher for RFA than for IRE, particularly for the maximum tested output parameters. The applicability of the newly designed balloon catheters was confirmed.
ER  -

BERNARD, Vladan, Tomáš ANDRAŠINA, D. ČERVINKA, J. MARTIŠ, P. PROCHÁZKA, Vojtěch MORNSTEIN and Vlastimil VÁLEK. A Thermographic Comparison of Irreversible Electroporation and Radiofrequency Ablation. \textit{IRBM}. New York: Elsevier Science INC., 2017, vol.~38, No~1, p.~26-33. ISSN~1959-0318. Available from: https://dx.doi.org/10.1016/j.irbm.2016.11.001.

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