MARQUES, Sérgio Manuel, Jan BREZOVSKÝ and Jiří DAMBORSKÝ. Role of Tunnels and Gates in Enzymatic Catalysis. In Svendsen, A. UNDERSTANDING ENZYMES: FUNCTION, DESIGN, ENGINEERING, AND ANALYSIS. USA: Pan Stanford Publishing, 2016, p. 421-463. prvni 1. ISBN 978-981-4669-32-0.
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Basic information
Original name Role of Tunnels and Gates in Enzymatic Catalysis
Authors MARQUES, Sérgio Manuel (620 Portugal, belonging to the institution), Jan BREZOVSKÝ (203 Czech Republic, belonging to the institution) and Jiří DAMBORSKÝ (203 Czech Republic, guarantor, belonging to the institution).
Edition USA, UNDERSTANDING ENZYMES: FUNCTION, DESIGN, ENGINEERING, AND ANALYSIS, p. 421-463, 43 pp. prvni 1, 2016.
Publisher Pan Stanford Publishing
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 10600 1.6 Biological sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW URL
RIV identification code RIV/00216224:14310/16:00088570
Organization unit Faculty of Science
ISBN 978-981-4669-32-0
UT WoS 000468289400013
Keywords in English Enzymes;lock-and-key model;
Tags AKR, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 23/4/2020 15:06.
Abstract
Understanding Enzymes: Function, Design, Engineering, and Analysis focuses on the understanding of enzyme function and optimization gained in the past decade, past enzyme function analysis, enzyme engineering, and growing insights from the simulation work and nanotechnology measurement of enzymes in action in vitro or in silico. The book also presents new insights into the mechanistic function and understanding of enzyme reactions, as well as touching upon structural characteristics, including X-ray and nuclear magnetic resonance (NMR) structural methods. A major focus of the book is enzyme molecules’ dependency on dynamic and biophysical environmental impacts on their function in ensembles as well as single molecules. A wide range of readers, including academics, professionals, PhD and master’s students, industry experts, and chemists, will immensely benefit from this exclusive book.
Links
GAP503/12/0572, research and development projectName: Konstrukce syntetické metabolické dráhy pro degradaci důležitého environmentálního polutantu proteinovým a metabolickým inženýrstvím
Investor: Czech Science Foundation
LH14027, research and development projectName: Nové koncepty a nástroje pro racionální design enzymů
Investor: Ministry of Education, Youth and Sports of the CR
LO1214, research and development projectName: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX)
Investor: Ministry of Education, Youth and Sports of the CR
4SGA8519, interní kód MUName: Rational design and engineering of enzyme gates (Acronym: BIOGATE)
Investor: South-Moravian Region, Incoming grants
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