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@inproceedings{1368635,
author = {Janousek, Oto and Ronzhina, Marina and Hejc, Jakub and Stračina, Tibor and Olejníčková, Veronika and Nováková, Marie},
address = {Washington},
booktitle = {Computing in Cardiology 2016},
editor = {Alan Murray},
keywords = {heart rate variability},
howpublished = {tištěná verze "print"},
language = {eng},
location = {Washington},
isbn = {978-1-5090-0896-4},
pages = {501-504},
publisher = {IEEE Computer Society},
title = {The Effect of Cardiac Filling on Heart Rate Variability in Rabbit Isolated Heart},
url = {http://ieeexplore.ieee.org/document/7868789/},
year = {2017}
}
TY - JOUR
ID - 1368635
AU - Janousek, Oto - Ronzhina, Marina - Hejc, Jakub - Stračina, Tibor - Olejníčková, Veronika - Nováková, Marie
PY - 2017
TI - The Effect of Cardiac Filling on Heart Rate Variability in Rabbit Isolated Heart
PB - IEEE Computer Society
CY - Washington
SN - 9781509008964
KW - heart rate variability
UR - http://ieeexplore.ieee.org/document/7868789/
L2 - http://ieeexplore.ieee.org/document/7868789/
N2 - Presence of heart rate variability (HRV) in isolated hearts is widely recognized; however, its mechanisms are still subject of debate. One of the possible explanations is that mechanoreceptors in cardiac tissue affect HRV. In order to evaluate possible dependence of HRV on heart mechanoreceptors activated during left ventricle filling, the HRV parameters in two perfusion modes of isolated heart were compared: Langendorff and working heart mode. Ten New Zealand rabbit isolated hearts were perfused (Krebs-Henseleit, 37°C, 85 mmHg) in Langendorff mode and consecutively in working heart mode (8 cmH2O preload, 60 cmfyO afterload). A total of 27 HRV parameters in time, frequency, geometric, and non-linear domain were computed. No significant differences (Wilcoxon signed rank test, p < 0.05) were found among all studied HRV parameters between Langendorff and working heart mode. The study confirms the presence of heart rate fluctuation in isolated hearts in both Langendorff and working heart modes. Results of statistical analysis show that heart rate fluctuation is irrespective to mechanical stimulation of heart during atrium and ventricle filling.
ER -
JANOUSEK, Oto, Marina RONZHINA, Jakub HEJC, Tibor STRAČINA, Veronika OLEJNÍČKOVÁ and Marie NOVÁKOVÁ. The Effect of Cardiac Filling on Heart Rate Variability in Rabbit Isolated Heart. In Alan Murray. \textit{Computing in Cardiology 2016}. Washington: IEEE Computer Society, 2017, p.~501-504. ISBN~978-1-5090-0896-4.
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